Author(s)

Bolade Thomas Adeyemo^1,2*, Tiamiyu Lateef Oloyede^2,3, Ayuba Victoria Ogeh², Cheikyula Joseph Orkuma²

¹Department of Veterinary Pathology, Faculty of Veterinary Medicine, University of Abuja, Abuja, Nigeria.
²Department of Fisheries and Aquaculture, College of Forestry and Fisheries, University of Agriculture Makurdi, Makurdi, Nigeria.

Fumonisin B₁ (FB₁) is produced by fungus of the genus Fusarium (Fusarium verticiloides and F. proliferatum), and occurs predominantly in maize. The consumption of feed contaminated with FB₁ has been reported to cause deleterious effects in some fish species. This study was designed to determine the effects of dietary FB₁ on growth and lipids profile of Clarias gariepinus. 450 juvenile catfish were stocked into 5 groups of tanks consisting of 3 tanks per group and fed one of five diets amended with FB₁ (0.0 mg; 10.0 mg; 20.0 mg; 40.0 mg and 80.0 mg FB₁/kg) for 56 days. At time point’s day 7, 14, 28 and 56, five fish were sampled from each tank weighted, length measured and bled for of lipids profile determinations. Results show that there was a significant reduction (P < 0.05), in the mean body length of the fish fed diets amended with various amounts of FB₁ compared with those fed control diet; also, there was a significant reduction (P < 0.05) in the weight gain of fishes fed diets amended with FB₁ compared with the control. The specific growth rate and the feed conversion ratio at 56 days shows fish fed 0.0 mg FB₁/kg had the highest specific growth rate (0.39 ± 0.14%/day) and the lowest feed conversion ratio (0.59 ± 0.01) whereas, fish fed 80.0 mg FB₁/kg had the least specific growth rate (0.07% ± 0.01%/day) and the highest feed conversion ratio (1.95 ± 0.11). Dietary FB₁ caused significant increases (P < 0.05) in serum cholesterol, HDL-C; LDL-C; triglycerides and the sphinganine-sphingosine ratio. Dietary FB₁ at an inclusion rate ≥ 20 mg FB₁/kg of diet produced significant reduction in weight gain and hyperlipidemia marked by hypercholesterolemia, increased blood high-density lipid cholesterol, increased blood low-density lipid cholesterol, elevated blood triglycerides and elevated sphinganine-sphingosine ratio.

Clarias gariepinus, Fumonisin B₁, Lipids Profile, Growth Performance, Cholesterol, Catfish

Adeyemo, B. , Oloyede, T. , Ogeh, A. and Orkuma, C. (2016) Growth Performance and Serum Lipids Profile of Clarias gariepinus Catfish Following Experimental Dietary Exposure to Fumonisin B₁. Open Journal of Veterinary Medicine, 6, 127-138. doi: 10.4236/ojvm.2016.68017.