Author(s)

Andrew K. Martusevich^1,2, Alexander G. Samodelkin¹, Lida K. Kovaleva³

¹Nizhny Novgorod State Agricultural Academy, Nizhny Novgorod, Russia.
²Privolzhsky Federal Medical Research Centre, Nizhny Novgorod, Russia.
³Kirov State Medical Academy, Kirov, Russia.

Free and initiated by 0.9% sodium chloride solution yielding of crystals was studied in the urine of the 35 healthy people. The metabolites—sodium lactate and sodium pyruvate—were superinduced into the dryable biological system in the increasing physiological concentrations. Regularities of the neogenic mixtures’ crystallization were revealed according to the metabolites dose. We showed the antagonistic tendencies in the parameters’ change at the increasing concentrations of the different metabolites—substratum of the enzyme’s opposite reactions—relying on the comparative estimation of the crystalloscopical and tezigraphical indices’ dynamics. Our own data and literature information brought us to a new conception of the biofluid’s stability as a crystallogenetic solution. According to it any substance injected into a dehydrated biological system proves to be a stabilizing or destabilizing agent which leads to a significant reorganization of the biocrystallogenesis. This phenomenon may cause a development of a management strategy of the biological crystallogenesis processes.

Crystallogenesis, Urine, Sodium Lactate, Sodium Pyruvate

Martusevich, A. , Samodelkin, A. and Kovaleva, L. (2016) Experimental Investigation of Reversible Modulation of Biological Fluid Crystallogenesis. Journal of Biomedical Science and Engineering, 9, 1-6. doi: 10.4236/jbise.2016.91001.