Open Journal of Nephrology

Volume 5, Issue 4 (December 2015)

ISSN Print: 2164-2842   ISSN Online: 2164-2869

Google-based Impact Factor: 0.42  Citations  

Renal Cortical Necrosis: An Unusual Complication of Plasmodium malariae Malaria

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DOI: 10.4236/ojneph.2015.54015    3,738 Downloads   4,162 Views  


Renal cortical necrosis (RCN) is anecdotal in malaria. To our knowledge, RCN secondary to Plasmodium malariae has not yet been published. We report a case of severe malaria complicated by RCN. A 29 year old Senegalese patient was transferred to our department for anuria in a context of severe malaria. The diagnosis was RCN secondary to a severe Plasmodium malariae malaria. Physical examination showed anuria, anaemic syndrome, haemorrhagic syndrome and a generally impaired condition. There was a normocytic normochromic anaemia aplastic, thrombocytopenia leukocytosis of 11.580/mm3, serum creatinine of 12.45 mg/dl and blood urea of 252 mg/dl. The Plasmodium malariae had been shown to thick blood film with high parasite density. The molecular study was able to confirm the infestation of this parasite. Treatment consisted of four haemodialysis sessions and antimalarial molecules. Initial evolution was favourable with a recovery through diuresis and a partial improvement in renal function. Given the persistence of impaired renal function, a renal biopsy was performed. This confirmed the RCN. At last consultation, he had no symptoms and his last glomerular filtration rate (GFR) was 30 mL/min/1.73 m2.

Cite this paper

Lemrabott, A. , Moustapha Cissé, M. , Seck, S. , Fary Ka, E. , Faye, M. , Ndongo, A. , Dial, C. , Keita, Y. , Fall, K. , Niang, A. and Diouf, B. (2015) Renal Cortical Necrosis: An Unusual Complication of Plasmodium malariae Malaria. Open Journal of Nephrology, 5, 99-104. doi: 10.4236/ojneph.2015.54015.

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