Effectiveness and Safety of Splenic Micro-wave Ablation Combined with Hepatic Ar-terial Chemoembolization for Hepatocellular Carcinoma Associated with Hypersplenism: A Prospective Study in 5 Patients ()
ABSTRACT
The aim was to prospectively
evaluate the efficacy and safety of splenic microwave ablation (MWA) combined with
transcatheter hepatic arterial chemoembolization (TACE) in treatment of hepatocellular carcinoma (HCC) associated with hypersplenism.
Five patients suffering from primary HCC associated with hypersplenism caused
by cirrhosis were received MWA combined with TACE. Follow-up examinations included calculation of peripheral blood cells (leukocytes,
platelets and red blood cells) and treatment-associated complications. After
treatment, leukocyte and platelet counts were significantly higher (P < 0.05)
than prior-treatment. Right upper quadrant pain occurred in 3 patients, fever occurred
in 4 patients, and mild nausea & vomiting occurred in 3 patients. Complications
such as pleural effusion, ascites, bacterial peritonitis, and variceal bleeding
did not occur after treatment. So, MWA combined with TACE is effective and safe
for the patients with HCC associated with hypersplenism caused by cirrhosis.
Share and Cite:
Wang, G. , Zhang, F. , Peng, S. , Zhang, T. , Lu, M. , Gu, Y. , Huang, J. and Gao, F. (2015) Effectiveness and Safety of Splenic Micro-wave Ablation Combined with Hepatic Ar-terial Chemoembolization for Hepatocellular Carcinoma Associated with Hypersplenism: A Prospective Study in 5 Patients.
Open Journal of Radiology,
5, 72-79. doi:
10.4236/ojrad.2015.52012.
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