These days, some manufacturing enterprises which are forced to diversify management enter Agri- Business and plant factory business, make an Innovation utilizing high research and development ability and enough capital. As Agri-Business Innovation in Japan, this study examinedNK Agri, a subsidiary company of Noritsu Koki, which is a motion picture producer and machinery maker, based on Industrial Cluster Theory and Diamond Model by Michael E. Porter. The important points to enter Agri-Business of manufacturing enterprises were summed up as below. 1) New coming manufacture enterprises can form Industrial Cluster with farmhouse and foods makers, and enhance productivity and competitiveness. 2) New coming manufacture enterprises can enhance productive efficiency by collaborating with orthodox farmhouses as important partners. 3) Re- search institutions such as universities and local government should support for forming and development of Agri Industrial Cluster by manufacture enterprises. Agri Industrial Cluster by manufacture enterprises can improve local economy, so local government should prepare for the system to expand support as a policy.