Author(s)

Ekkasit Tharavichitkul^1*, Sukon Prasitwattanaseree², Cholthicha Thipmate², Somvilai Chakrabandhu¹, Pitchayaponne Klunklin¹, Wimrak Onchan¹, Razvan M. Galalae³, Imjai Chitapanarux¹

¹The Division of Therapeutic Radiology and Oncology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
²Biostatistics and Applied Statistics Laboratory, Department of Statistics, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand.
³Faculty of Medicine, Christian-Albretch University, Kiel, Germany.

Purpose: To report the retrospective study of using intravaginal brachytherapy as adjuvant monotherapy for endometrial cancer. Materials and Methods: From 2001-2009, 47 patients who received completely surgical staging for endometrial carcinoma and were designed by multidisciplinary team were enrolled. All patients received intravaginal brachytherapy (IVBT) with the dose of 5.5 - 7 Gy in 2 - 6 fractions. The treatment results and late toxicities were evaluated and recorded. Results: At the median follow-up time of 44 months, the local control, disease-free survival, metastasis-free survival and overall survival rates were 100%, 97.9%, 97.9% and, 97.9%, respectively. Only age showed the statistical significance with the p-value of 0.046. Two patients (4.3%) developed late genitourinary toxicity. Conclusion: The using of adjuvant IVBT as monotherapy for endometrial carcinoma is feasible.

Endometrial Cancer, Adjuvant, Brachytherapy, Monotherapy

Tharavichitkul, E. , Prasitwattanaseree, S. , Thipmate, C. , Chakrabandhu, S. , Klunklin, P. , Onchan, W. , Galalae, R. and Chitapanarux, I. (2015) Treatment Results of Adjuvant Brachytherapy as Monotherapy in Endometrial Cancer: A Retrospective Study from Faculty of Medicine, Chiang Mai University. Journal of Cancer Therapy, 6, 34-39. doi: 10.4236/jct.2015.61005.