OJAnes> Vol.4 No.7, July 2014

Author(s)

José Pomares, Gustavo Mora-García, Roberto Palomino, Yéssika De León, Claudio Gómez-Alegría, Doris Gómez-Camargo

Anesthesiology and Reanimation Department, Faculty of Medicine, University of Cartagena, Cartagena de Indias, Colombia.
Faculty of Medicine, University of Cartagena, Cartagena de Indias, Colombia.
Pharmacy Department, Faculty of Sciences, National University of Colombia, Bogotá, Colombia.
Tropical Medicine Doctorate Program, Faculty of Medicine, University of Cartagena, Cartagena de Indias, Colombia.

Background: Metabolic syndrome (MS) is a constellation of factors associated with increased risk of developing cardiovascular diseases and Diabetes Mellitus. Despite of the many studies related to MS, little is known about its impact on scenarios such as surgical anesthesia. Objective: To examine the correlation between demographic and metabolic variables with the occurrence of perioperative complications in patients with MS undergoing scheduled surgeries using a spinal anesthesia technique in the surgery department at the University Clinic San Juan de Dios in Cartagena de Indias, Colombia. Methods: Observational, analytical, cross-sectional, single-center study of 150 subjects with MS and 150 control subjects. Perioperative complications, socio-demographic, hemodynamic and respiratory variables were registered. Groups were compared using t test, Fisher’s exact test or Chi-square, as appropriate. We applied a logistic multiple regression model, adjusted by backward stepwise at 0.25 and forward at 0.05, to find possible incompatible associations. p value < 0.05 was considered significant. Results: There were significant differences between groups in age, American Society of Anesthesiologists physical status classification, frequency of diseases associated to MS and perioperative complications. There were no cases of mortality among patients. There was statistically significant difference between the two groups for intraoperative hypotension and hypertension with p values of <0.0001 and 0.034. Among postoperative complications there was statistically significant difference in pain (13.3% vs 5.3% in patients without MS) and nausea and/or postoperative vomiting (8% vs 2% in patients without MS) with a p value of 0.027 and 0.015 (by Fisher) respectively. Conclusions: Metabolic abnormalities in MS are a risk factor for developing complications in the perioperative period of patients scheduled for surgeries using the subarachnoid anesthesia technique. Accordingly, it is appropriate to implement health intervention strategies by the surgical team, aiming at their prevention and management.

Metabolic Syndrome X, Insulin Resistance, Spinal Anesthesia, Abdominal Obesity, Perioperative Period

Pomares, J. , Mora-García, G. , Palomino, R. , De León, Y. , Gómez-Alegría, C. and Gómez-Camargo, D. (2014) Metabolic Syndrome and Perioperative Complications during Scheduled Surgeries with Spinal Anesthesia. Open Journal of Anesthesiology, 4, 167-176. doi: 10.4236/ojanes.2014.47024.