Injection wells have been used for disposal of fluids for nearly 100 years. Design of injection well systems has advanced over the years, but environmental concerns due to the potential for migration of injected fluids remain. Fluids range from hazardous materials, to mining waste to treated wastewater. This paper presents an evaluation of wells injecting treated wastewater to assess which create the greatest risk to migration potential. Prior studies have looked at the risks of Class I injection wells for wastewater disposal, but limited data were available at that time. This research involved collecting data and evaluating the differences as a means to predict the potential for fluid migration in the wells. There were four issues that might portend migration: well depth-shallower wells tended to have more migration; the tightness of the confining unit immediately above the injection zone; well age; and the use of tubing and packers. Florida is moving away from tubing and packer wells which may be an indicative of this issue. The results provide a pathway to investigate injection wells in other states.