Author(s)

Alfred Friday Ehiaghe, Dennis E. Agbonlahor, Youtchou Mirabeau Tatfeng, Folarin Onikepe, Faith Efosa Oviasogie, Joy Imuetinya Ehiaghe

Department of Hematology, Igbinedion University, Okada, Nigeria.
Department of Medical Laboratory Science, Niger Delta University, Wilberforce Island, Nigeria.
Department of Microbiology, University of Benin, Benin City, Nigeria.
Lahor Research Laboratory, Benin City, Nigeria.

C reactive protein is sensitive physiological biomarkers of sub clinical inflammation associated with hyperglycemia. The aim of this study is to determine the fasting serum C reactive protein level in type 2 diabetes mellitus patients attending diabetic clinic in Benin City, Nigeria. The population sample consists of 142 subjects. 71 patients were known type 2 diabetes mellitus, while the other 71 were age matched control subjects. Fasting glucose and C reactive protein were estimated using glucose oxidase method and ELISA method respectively. The age group that has the highest number of type 2 diabetes mellitus was 41 - 50 (64% of males and 36% of the females). Our finding revealed that C reactive protein and serum glucose level of type 2 Diabetes mellitus in both females and males show a statistically significant increase as compared with age matched Control subjects, (P < 0.05). An elevation of serum C-reactive protein was demonstrated in both males and females type 2 diabetes mellitus in Benin City, Nigeria. These data support a possible role of inflammatory biomarkers in diabetogenesis.

C Reactive Proteins; Hyperglycemia; Inflammatory Biomarkers; Diabetogenesis

Ehiaghe, A. , Agbonlahor, D. , Tatfeng, Y. , Onikepe, F. , Oviasogie, F. and Ehiaghe, J. (2013) Serum C reactive protein level in type 2 diabetes mellitus patients attending diabetic clinic in Benin City, Nigeria. Journal of Diabetes Mellitus, 3, 168-171. doi: 10.4236/jdm.2013.34026.