Possibilities of transcatheter treatment of patients after extensive ischemic stroke ()
ABSTRACT
The research investigates the efficacy of brain transcatheter
laser revascularization in patients who have had extensive ischemic stroke.
1125 patients aged 29 - 81 (average age 75) with cerebral atherosclerosis were examined. The examination plan included: CT brain scan, magnetic resonance
imaging (MRI), brain scintigraphy (SG), rheoencephalography (REG), cerebral
multi-gated angiography (MUGA), laboratory tests, assessment of severity of
dementia (CDR), cognitive impairment (MMSE) and activities of daily living
(IB). 93 patients suffered extensive
ischemic stroke of whom 7 (7.53%) had 10 - 15 IB points, 25 (26.88%)—20 -
30 IB points, 61 (65.59%)—35 - 45 IB points. 69 patients underwent transcatheter
treatment (Test Group). 24 patients underwent conservative treatment (Control
Group). High-energy laser systems were used for revascularization of major
intracranial arteries; lowenergy laser systems were used for revascularization of distal intracranial branches. Test Group: 67 (97.10%) patients had good immediate angiographic outcome manifested in the
restoration of lumen and patency of the affected vessels as well as in
collateral revascularization. 12 - 24 months later the following positive trend
was observed: 14 (20.59%) patients demonstrated
good clinical outcome (IB 90 - 100); 26 (38.24%) patients had
satisfactory clinical outcome (IB 75 - 85); 28 (41.18%) patients showed
relatively satisfactory clinical outcome (IB 60 - 70); relatively positive clinical
outcome (IB < 60) was not obtained in any case. Control Group: 4 (16.67%) patients
showed relatively satisfactory clinical
outcome (IB 60 - 70), relatively positive clinical outcome (IB < 60)
was achieved in 20 (83.33%) cases. Evaluating the data obtained, it can be
concluded that the method of transluminal laser revascularization of cerebral
blood vessels is an effective one for the treatment of extensive ischemic
strokes. The effect is maintained for a long time; it causes regression of
mental, intellectual and motor disorders, promotes regression of post-stroke
dementia and significantly improves the
quality of life, which makes it noticeably different from the conservative
methods of treatment.
Share and Cite:
Maksimovich, I. (2013) Possibilities of transcatheter treatment of patients after extensive ischemic stroke.
World Journal of Neuroscience,
3, 171-185. doi:
10.4236/wjns.2013.33022.