Volume 2, Issue 2 (June 2013)

ISSN Print: 2327-0799   ISSN Online: 2327-0802


Photoisomerization of Provitamin D in Hydrogel Matrix

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DOI: 10.4236/soft.2013.22003    5,433 Downloads   10,050 Views  Citations


Study of interfacial processes between incorporated biomolecules and hydrogel matrix is of primary importance for the application of synthetic hydrogels as biomaterials, sensors, etc. Their hydrophilic nature, however, hampers fat-soluble biomolecule incorporation. We synthesized N-isopropylacrylamide (NIPAAm)- and Acrylamide (AA)-based hydrogels with hydrophilic-lipophilic balance that under specific conditions permit homogeneous incorporation of provitamins D3(7-dehydrocholesterol) and D2(ergosterol) dissolved in ethanol. Similarity of provitamins D photoisomerization in such hydrogel matrices with the photoreaction in ethanol shows great potential of the novel material for personal dosimetry of biologically active ‘antirachitic’ UV radiation.


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Terenetskaya, I. , Samchenko, Y. , Orlova, T. , Pasmurceva, N. , Kapinos, P. , Boldeskul, I. and Ulberg, Z. (2013) Photoisomerization of Provitamin D in Hydrogel Matrix. Soft, 2, 8-12. doi: 10.4236/soft.2013.22003.

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