Open Journal of Epidemiology

Volume 3, Issue 2 (May 2013)

ISSN Print: 2165-7459   ISSN Online: 2165-7467

Google-based Impact Factor: 0.57  Citations  

Decreasing serum uric acid levels are associated with improving estimated glomerular filtration rate (eGFR) in Japanese women

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DOI: 10.4236/ojepi.2013.32007    3,503 Downloads   5,168 Views  

ABSTRACT

The aim of this study was to investigate the link between changes in a subject’s serum uric acid levels and the estimated glomerular filtration rate (eGFR) in Japanese women. We used data for 161 Japanese women (49.8 ± 11.7 years) with a 1-year follow up. eGFR was defined by a new equation developed for Japan. eGFR was negatively correlated with serum uric acid levels (r = -0.402, p < 0.0001) at baseline. Subjects were given advice for dietary and lifestyle improvement. At the 1-year follow up, abdominal circumference and systolic blood pressure (SBP) were significantly improved. However, uric acid and eGFR did not change. The changes in eGFR were negatively correlated with uric acid (r = -0.475, p < 0.0001). A decrease in serum uric acid levels was associated with improving eGFR in Japanese women.

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Miyatake, N. , Shikata, K. , Makino, H. and Numata, T. (2013) Decreasing serum uric acid levels are associated with improving estimated glomerular filtration rate (eGFR) in Japanese women. Open Journal of Epidemiology, 3, 40-43. doi: 10.4236/ojepi.2013.32007.

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