Engineering
Volume 4, Issue 10 (October 2012)
ISSN Print: 1947-3931 ISSN Online: 1947-394X
Google-based Impact Factor: 0.66 Citations
Efficacy and Safety of Nasal Administration of “Na-no-L-DOPA” Based on PLGA Nanoparticles ()
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ABSTRACT
Inclusion of L-DOPA, the standard Parkinson’s disease medication, into polymeric particles (PLGA) results in optimization the drug metabolism and increasing its bioavailability, significantly increases of physical endurance, better coordination and lower anxiety in Wistar rats, when chronically administered nasally.
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