Author(s)

Lokesh A. Shastri, Samundeeswari L. Shastri, Manohar V. Kulkarni, Vivek K. Gupta, Sanjeev Goswami

P. G. Department of Chemistry, Karnatak University, Dharwad, India.
P. G. Department of Physics, University of Jammu, Jammu Tawi, India.

The present study reports the reaction of 4-bromomethylcoumarins with salicylidineaniline in acetone with two equivalents of potassium carbonate resulted in the formation of title compounds at room temperature via intramolecular aldolization. The obtained compound is thermodynamically and kinetically stable with highly stereoselective and excellent yield.

Aldol Reaction; Stereoselective; Intramolecular; Mild Base; 4-Bromomethylcoumarins; Dihydrobenzofurans

L. A. Shastri, S. L. Shastri, M. V. Kulkarni, V. K. Gupta and S. Goswami, "Stereoselective Synthesis of cis-Substituted-3’-anilino-2’, 3’-dihydro-4-2’-benzo[b]furanylcoumarins via Intramolecular Aldol Reactions," International Journal of Organic Chemistry, Vol. 2 No. 1, 2012, pp. 44-48. doi: 10.4236/ijoc.2012.21008.