Author(s)

Ngardjibem Djita^1*, Ibrahima Sory2 Sylla^1,2, Aissatou Barry², Murielle Ahodakin¹, Djibril Sylla², Elhadj Yaya Balde², Mamadou Bachir Bah², Houzeiph Abdou Lassissi¹, Alpha Kone², Sana Soumra², Mamadou Aliou Balde², Mariame Beavogui², Mamadou Dadhi Balde², Noura Feniche¹

¹Cardiology Department, Alençon-Mamers Intercommunal Hospital, Alençon, France.
²Gamal Abdel Nasser University of Conakry, Conakry, Republic of Guinea.

Introduction: Cardiac amyloidosis is a rare and under-diagnosed disease. The objective of this study was to collect cases of cardiac amyloidosis in patients hospitalized in the cardiology department of the Centre Hospitalier Intercommunal Alençon-Mamers (CHICAM). Patients and Methods: This was a retrospective descriptive study of the records of patients diagnosed with cardiac amyloidosis. The study took place in the cardiology department of the CHICAM over 12 months (from January 1, 2020 to December 31, 2020). We included the files of patients in whom the diagnosis of cardiac amyloidosis was confirmed on the basis of clinical, echocardiographic, biological, scintigraphic and cardiac MRI evidence. Results: Seven patients were included. The mean age was 86.71 years. Six men for one woman. Most of the patients were in heart failure. There was one case of periorbital ecchymosis. Troponinemia was increased in three patients, NTproBNP was always high with a mean of 1000 ng/L. Cardiac echography showed a hyperbright septum in four cases, concentric hypertrophy of the left ventricle with a mean interventricular septum in diastole of 13.85 mm. Six cases were senile transthyretin amyloidosis (TTR), one case was mutated transthyretin amyloidosis (TTRm). Two cases of death were noted. Conclusion: Cardiac amyloidosis has a poor prognosis due to delayed diagnosis.

Cardiac Amyloidosis, Echocardiography, Heart Failure, Myocardial Scintigraphy

Djita, N. , Sylla, I. , Barry, A. , Ahodakin, M. , Sylla, D. , Balde, E. , Bah, M. , Lassissi, H. , Kone, A. , Soumra, S. , Balde, M. , Beavogui, M. , Balde, M. and Feniche, N. (2022) Cardiac Amyloidosis: A Case Report of Seven Patients. World Journal of Cardiovascular Diseases, 12, 160-167. doi: 10.4236/wjcd.2022.123017.