Open Journal of Genetics

Volume 11, Issue 3 (September 2021)

ISSN Print: 2162-4453   ISSN Online: 2162-4461

Google-based Impact Factor: 0.21  Citations  

Isodicentric Ychromosome: Case Study

HTML  XML Download Download as PDF (Size: 13681KB)  PP. 56-62  
DOI: 10.4236/ojgen.2021.113006    216 Downloads   1,497 Views  

ABSTRACT

Isodicentric chromosomes are a frequently appearing abnormality in the human Y chromosome. Making predictions regarding the phenotypic outcomes of a variety of duplications/deletions in the dicentric Y chromosome generally depends on the breakpoint location and also the level of mosaicism (45, X cell lines); in certain instances, these may not be detected and result in variations running between male, abnormal female, or ambiguity in individual genitalia. A referral was received from a urology clinic concerning two patients, one aged 34 and one aged 35, with a request to investigate reasons for infertility: G-banded karyotyping and fluorescence in situ hybridization (FISH) revealed the presence of an isodicentric Y chromosome.

Share and Cite:

Wathnani, A. , Tashkandi, S. , Saidi, K. , Muteiri, K. and Enezi, W. (2021) Isodicentric Ychromosome: Case Study. Open Journal of Genetics, 11, 56-62. doi: 10.4236/ojgen.2021.113006.

Cited by

No relevant information.

Copyright © 2024 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.