Author(s)

Abderrazzak Bertal¹, Alberic Fabrice Bocco^1*, Ismaïl Mahazou¹, Asmaa Harrach², Nihad da Silva³, Mohamed Yassine Haouas¹, Khadija Ibahioin^1,4, Said Hilmani¹, Mehdi Karkouri³, Abdelhakim Lakhdar^1,4

¹Department of Neurosurgery, Ibn Rochd University Hospital Center, Casablanca, Morocco.
²Department of Hematology and Pediatric Oncology, Ibn Rochd University Hospital Center, Casablanca, Morocco.
³Department of Pathology, Ibn Rochd University Hospital Center, Casablanca, Morocco.
⁴Laboratory of Research on Neurologic and Neurosensorial Diseases and Handicap, Faculty of Medicine, Hassan II University, Casablanca, Morocco.

Medulloblastoma (MB) is a malignant brain tumor with a usual potential for leptomeningeal spread. Intramedullary metastases of MB are rare and there are very few cases reported in the literature. Here, we report the case of an 18-year-old man with intramedullary spinal cord metastasis of MB occurring 9 years after the first diagnosis. The patient presented a 2-month history of progressive weakness in both lower limbs associated with urinary incontinence. Magnetic resonance imaging (MRI) demonstrated a large intramedullary spinal cord tumor extending from T10 to L1. The patient underwent surgical decompression and adjuvant therapy. Histological examination confirmed the diagnosis of classic MB metastasis. Postoperatively, the neurological status was stationary. Intramedullary metastasis of medulloblastoma is rare and difficult to manage with a poor prognosis. Comprehensive studies on the medulloblastoma dissemination mechanisms and clinical trials are needed to assess combined therapeutic approaches on metastases of MB.

Medulloblastoma, Intramedullary Metastasis, Classic, Spinal Cord

Bertal, A. , Bocco, A. , Mahazou, I. , Harrach, A. , Silva, N. , Haouas, M. , Ibahioin, K. , Hilmani, S. , Karkouri, M. and Lakhdar, A. (2021) Intramedullary Metastasis of Medulloblastoma: A Case Report. Open Journal of Modern Neurosurgery, 11, 90-96. doi: 10.4236/ojmn.2021.112010.