With the spread of the epidemic, the problem of online teaching has become one of the focuses of the whole society. As the organizer of online teaching, the teaching effect of university teachers should be paid more attention to. This study takes university teachers as the research object, understands the current situation of online teaching, expounds the influencing factors of teaching effect, and also analyzes the correlation among teachers’ adaptability, teachers’ attitude and teaching effect. There is a positive correlation among teachers’ adaptability, teachers’ attitude and teaching effect. The prediction model of the relationship is constructed between teachers’ attitude and teaching effect.