Author(s)

Anil K. Kinage, Pravin P. Upare, Anandkumar B. Shivarkar, Sunil P. Gupte

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The nucleophilic ring opening of epoxides with amines is a well known route for the synthesis of β-amino alcohols. The use of carbonates offers significant advantages over epoxides as they are far less hazardous materials, safe for handling, do not require high-pressure equipment and most notably the possibility of solvent less reactions. In this work, utilization of zeolite as host catalyst in the reaction media for synthesis of β-amino alcohols without using solvent is reported.

β-Amino Alcohol, Proplylene Carbonate, Zeolite, Catalyst, Chemo-Selectivity

A. Kinage, P. Upare, A. Shivarkar and S. Gupte, "Highly Regio-Selective Synthesis of β-Amino Alcohol by Reaction with Aniline and Propylene Carbonate in Self Solvent System over Large Pore Zeolite Catalyst," Green and Sustainable Chemistry, Vol. 1 No. 3, 2011, pp. 76-84. doi: 10.4236/gsc.2011.13013.