Author(s)

Masahiro Komeda¹, Ayana Ozaki¹, Keita Hayashi¹, Michinori Sumimoto¹, Kenji Hori¹, Tsunemi Sugimoto², Hidetoshi Yamamoto^1*

¹Graduate School of Science and Engineering, Yamaguchi University, Ube, Japan.
²Ube Laboratory, Ube Industries, Ltd., Ube, Japan.

The Beckmann rearrangement of cyclohexanone oxime was achieved by the combined use of cobalt salt and Lewis acids co-catalysts (each 10 mol%). Various combinations of cobalt salts and Lewis acids gave lactams in a satisfactory yield under mild conditions. This method makes it possible to reduce undesirable byproducts.

Beckmann Rearrangement, Cycloalkanone Oximes, Lactam, Cobalt Catalysts, Lewis Acids

Komeda, M. , Ozaki, A. , Hayashi, K. , Sumimoto, M. , Hori, K. , Sugimoto, T. and Yamamoto, H. (2015) The Effective Catalyst (Cobalt Salt/Lewis Acid) for Beckmann Rearrangement of Cycloalkanone Oximes to Lactams under Mild Conditions. International Journal of Organic Chemistry, 5, 57-62. doi: 10.4236/ijoc.2015.52007.