In digital substations with power transformers, the key to implementation of line differential protection is synchronization of electrical quantities at both two sides. System framework of current differential protection for lines between digital substations is analyzed briefly, as well as the necessity of demand for time synchronization. Principle of time synchronization based on GPS and IEEE1588 PTP (Precision Time Protocol) are introduced. Time synchronization of current differential protection between digital substations based on IEC61850 is discussed. This paper puts forward two solution schemes of time synchronization, analyzes their advantages and disadvantages respectively, and points out that the development direction of time synchronization of differential protection between digital substations is IEEE1588 PTP.