Author(s)

Iadeishisha Kharbangar, Md. Rumum Rohman, Hormi Mecadon, Bekington Myrboh

Department of Chemistry, North-Eastern Hill University (NEHU), Shillong, India.

KF-Al₂O₃ as a recyclable basic catalyst for the three-component synthesis of 4H-pyran derivatives by the reaction of aldehydes, malononitrile and active methylene dicarbonyl compounds in ethanol at room temperature is described. The protocol is environmentally benign and offers rapid access to a wide array of 4H-pyran heterocycles in good to excellent yields.

4H-Pyran derivatives; Ethanol; KF-Al₂O₃; Room Temperature; Three-Component

I. Kharbangar, M. Rohman, H. Mecadon and B. Myrboh, "KF-Al₂O₃ as an Efficient and Recyclable Basic Catalyst for the Synthesis of 4H-Pyran-3-carboxylates and 5-Acetyl-4H-pyrans," International Journal of Organic Chemistry, Vol. 2 No. 3, 2012, pp. 282-286. doi: 10.4236/ijoc.2012.23038.