Prof. Robert Geoffrey Cooper

Bablake Grammar School, Coventry University

Manchester Medical School

Email: robert.g.cooper@manchester.ac.uk   

Qualifications

1986    M.D., Manchester University, UK

Publications(Selected)

1. Cooper RG, Evans DAP, Whibley EJ.  Polymorphic hydroxylation of perhexiline maleate in man.  J Med Genet 1984, 21: 27-33. 
2. Cooper RG, Dockray GJ, Calam J, Walker R.  Acid and gastrin responses during intragastric titration in normal subjects and duodenal patients with G-cell hyperfunction.  Gut 1985, 26: 232-236. 
3. Cooper RG, Carroll N, Belchetz PE.  Aspiration of oral contents in Parkinson's Disease.  A case report.  S Afr Med J 1985, 68: 344-345. 
4. Cooper RG, Harper G, Price AH, Evans DAP, Lockhart D. Simultaneous determination of perhexiline and its monohydroxymetabolites in biological fluids by gas chromatography-electron-capture detection. J Chromatogr 1986, 381: 305-314. 
5. Cooper RG, Evans DAP, Price AH.  Studies on the metabolism of perhexiline in man.  Eur J Clin Pharmacol 1987, 32: 569-576. 
6. Cooper RG, Edwards RHT, Gibson H, Stokes M. Human muscle fatigue: frequency dependence of excitation and force generation. J Physiol 1988, 397: 585-599. 
7. Cooper RG, Stokes MJ, Edwards RHT, Stark RD. Absence of excess peripheral muscle fatigue during beta-adrenoceptor blockade.  Br J Clin Pharmacol 1988, 25: 405-415. 
8. Cooper RG, Jenkins SA, Evans DA, Price AH. The enterohepatic circulation of perhexiline metabolites in the male Wistar rat.  Zenobiotica 1988, 18: 389-396. 
9. Stokes MJ, Newsholme SJ, Cooper RG, Montgomery A, Edwards, RHT. Technique for physiological examination of canine skeletal muscle in vivo. Res Vet Sci 1988, 45: 127-129
10. Cooper RG, Stokes MJ, Edwards RHT. Physiological characterisation of the “warm up” effect of activity in patients with myotonic dystrophy.  J Neurol Neurosurg Psychiatry 1988, 51: 1134-1141.
11. Gibson H, Cooper RG, Stokes MJ, Edwards RHT. Mechanisms resisting fatigue in isometrically contracting human skeletal muscle.  Q J Exp Physiol 1988, 73: 903-914
12. Stokes MJ, Cooper RG, Edwards RHT. Normal muscle strength and fatiguability in patients with effort syndromes.  Br Med J 1988, 297:1014-1017.
13. Cooper RG, Stokes MJ, Edwards RHT. Myofibrillar activation failure in McArdle’s disease.  J Neurol Sci 1989, 93:1-10.
14. Stokes MJ, Edwards RHT, Cooper RG. Effect of low-frequency fatigue on human muscle strength and fatiguability during subsequent stimulated activity.  Eur J Appl Physiol 1989, 59: 278-283
15. Bate AS, Sidebottom D, Cooper RG, Loftus M, Chattopadhyay C, Grennan DM. DNA variants of alpha-1-antitrypsin in rheumatoid arthritis with and without pulmonary complications. Disease Markers 1990, 8: 317-321
16. Cooper RG, Taylor CM, Choo JJ, Weiss JB. Elevated endothelial-cell-stimulating angiogenic factor activity in rodent glycolytic skeletal muscles. Clin Sci 1991, 81: 267-270
17. Cooper RG, Mitchell WS, Illingworth KJ, Forbes WS, Gillespie JE, Jayson MIV. The role of epidural fibrosis and defective fibrinolysis in the persistence of post-laminectomy back pain. Spine 1991, 16: 1044-1048
18. Holt I, Cooper RG, Hopkins S. Relationships between local inflammation, interleukin-6 concentration and the acute phase protein response in arthritis patients. Eur J Clin Invest 1991, 21: 479-484
19. Cooper RG, Freemont AJ, Fitzmaurice R, Alani SM, Jayson MIV. Paraspinal muscle fibrosis, a specific pathological component in ankylosing spondylitis. Ann Rheum Dis 1991, 50: 755-759
20. Cooper RG, Mitchell WS, Illingworth KJ, Jayson MIV. Fibrinolytic enhancement with stanozolol fails to improve symptoms and signs in patients with post-surgical back pain. Scand. J Rheumatol 1991, 20: 414-418
21. Cooper RG, Freemont AJ, Riley M, Holt PJL, Anderson DC, Jayson MIV. Bone abnormalities and severe arthritis in pachydermoperiostitis.Ann Rheum Dis 1992, 51: 416-419
22. Lee DJ, Stokes MJ, Taylor RJ, Cooper RG. Electro and acoustic myography for noninvasive assessment of lumbar paraspinal muscle function.  Eur J Appl Physiol 1992, 64: 199-203
23. Hayes ME, Bayley D, Still P, Palit J, Denton J, Freemont AJ, Cooper RG, Mawer EB. Differential metabolism of 25-hydroxyvitamin D3 by cultured synovial fluid       macrophages and fibroblast-like cells from patients with arthritis. Ann Rheum Dis 1992, 51: 220-226.
24. Cooper RG, Hollis S, Jayson MIV. Gender variation in spinal and paraspinal structures in chronic back pain patients. Clin Biomechan 1992, 7: 120-124
25. Cooper RG, St Clair Forbes W, Jayson MIV. Radiographic demonstration of paraspinal muscle wasting in patients with chronic low back pain. Br J Rheumatol  1992, 31: 389-394
26. Hayes ME, Rai A, Cooper RG, Bayley D, Freemont AJ, Mawer EB. Inhibition by prostaglandin E1 and E2 of 1,25-dihydroxyvitamin D3 synthesis by synovial fluid macrophages from arthritic joints. Ann Rheum Dis 1992, 51: 632-637
27. Cooper RG, Stokes MJ, Morris G, Jayson MIV. Selective changes in multifidus dimensions in patients with chronic low-back pain. Eur Spine J 1992, 1: 38-42
28. Holt I, Cooper RG, Denton J, Meager A, Hopkins SJ. Cytokine inter-relationships and their association with disease activity in arthritis.  Br J Rheumatol 1992, 31: 725-733
29. Jeracitano D, Cooper RG, Lyon LJ, Jayson MIV. Abnormal temperature control suggesting sympathetic dysfunction in the shoulder skin of patients with frozen shoulder.  Br J Rheumatol 1992, 31: 539-542
30. Cooper RG, Stokes MJ, Sweet C, Taylor RJ, Jayson MIV. Increased central drive during fatiguing contractions of the paraspinal muscles in patients with chronic low back pain. Spine 1993, 18: 610-616.