Dr. Guozheng Wang
Institute of Infection, Veterinary & Ecological Sciences
Faculty of Health and Life Sciences
University of Liverpool, UK
Email: wangg@liv.ac.uk, G.Wang@liverpool.ac.uk
Qualifications
1998-2002 Ph.D., University of Liverpool, Liverpool, UK
1985-1988 M.D., Southeast University, Nanjing, China
1977-1982 MBChB., Southeast University, Nanjing, China
Publications (Selected)
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Toh, J. M., Yong, J., Abrams, S. T., Wang, L., Schofield, J., Lane, S., ... & Wang, G. (2024). Fibrinogen binding to histones in circulation protects against adverse cellular and clinical outcomes. Journal of Thrombosis and Haemostasis.
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Abrams, S. T., Du, M., Shaw, R. J., Johnson, C., McGuinness, D., Schofield, J., ... & Wang, G. (2024). Damage-associated cellular markers in the clinical and pathogenic profile of vaccine-induced immune thrombotic thrombocytopenia. Journal of Thrombosis and Haemostasis, 22(4), 1145-1153.
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Ismail, T. M., Crick, R. G., Du, M., Shivkumar, U., Carnell, A., Barraclough, R., ... & Wang, G. (2023). Targeted Destruction of S100A4 Inhibits Metastasis of Triple Negative Breast Cancer Cells. Biomolecules, 13(7), 1099.
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Abrams, S. T., Alhamdi, Y., Zi, M., Guo, F., Du, M., Wang, G., ... & Toh, C. H. (2023). Extracellular Histone-Induced Protein Kinase C Alpha Activation and Troponin Phosphorylation Is a Potential Mechanism of Cardiac Contractility Depression in Sepsis. International Journal of Molecular Sciences, 24(4), 3225.
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Abrams, S. T., Wang, L., Yong, J., Yu, Q., Du, M., Alhamdi, Y., ... & Wang, G. (2022). The importance of pore-forming toxins in multiple organ injury and dysfunction. Biomedicines, 10(12), 3256.
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Alsabani, M., Abrams, S. T., Cheng, Z., Morton, B., Lane, S., Wang, G., ... & Toh, C. H. (2022). Reduction of NETosis by targeting CXCR1/2 reduces thrombosis, lung injury, and mortality in experimental human and murine sepsis. British journal of anaesthesia, 128(2), 283-293.
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Abrams, S. T., Su, D., Sahraoui, Y., Lin, Z., Cheng, Z., Wang, G., ... & Toh, C. H. (2021). Assembly of alternative prothrombinase by extracellular histones initiates and disseminates intravascular coagulation. Blood, The Journal of the American Society of Hematology, 137(1), 103-114.
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Wang, Z., Cheng, Z., Abrams, S. T., Lin, Z., Yates, E. D., Yu, Q., ... & Wang, G. (2020). Extracellular histones stimulate collagen expression and potentially promote liver fibrogenesis via TLR4-MyD88 signalling pathway. bioRxiv, 2020-09.
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Cheng, Z., Abrams, S. T., Austin, J., Toh, J., Wang, S. S., Wang, Z., ... & Wang, G. (2020). The central role and possible mechanisms of bacterial DNAs in sepsis development. Mediators of Inflammation, 2020(1), 7418342.
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Cheng, Z., Abrams, S. T., Toh, J., Wang, S. S., Wang, Z., Yu, Q., ... & Wang, G. (2020). The critical roles and mechanisms of immune cell death in sepsis. Frontiers in immunology, 11, 1918.
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Cheng, Z., Abrams, S. T., Toh, J., Wang, S. S., Downey, C., Ge, X., ... & Toh, C. H. (2020). Complexes between C-Reactive Protein and Very Low Density Lipoprotein Delay Bacterial Clearance in Sepsis. The Journal of Immunology, 204(10), 2712-2721.
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Du, M., Wang, G., Barsukov, I. L., Gross, S. R., Smith, R., & Rudland, P. S. (2020). Direct interaction of metastasis-inducing S100P protein with tubulin causes enhanced cell migration without changes in cell adhesion. Biochemical Journal, 477(6), 1159-1178.
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Cheng, Z., Abrams, S. T., Alhamdi, Y., Toh, J., Yu, W., Wang, G., & Toh, C. H. (2019). Circulating histones are major mediators of multiple organ dysfunction syndrome in acute critical illnesses. Critical care medicine, 47(8), e677-e684.
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Moxon, C. A., Alhamdi, Y., Storm, J., Toh, J. M., Ko, J. Y., Wang, G., ... & Toh, C. H. (2019). Parasite histones mediate leak and coagulopathy in cerebral malaria. bioRxiv, 563551.
Profile Details
https://orcid.org/0000-0001-5525-3548
https://www.liverpool.ac.uk/people/guozheng-wang
https://sciprofiles.com/profile/1159139