Dr. Qingshan Qu

Nelson Institute of Environmental Medicine

New York University School of Medicine, USA

Research Associate Professor



1972 Resident, Department of Occupational Diseases, Third Teaching Hospital, Beijing Medical College

1969 MD, Beijing Medical College, China (Current Peking University Health Science Center)

Publications (Selected)

  1. Arita A, Munoz A, Chervona Y, Niu J, Qu Q, Zhao N, Ruan Y, Kiok K, Kluz T, Sun H, Clancy HA, Shamy M, Costa M. Gene expression profiles in peripheral blood mononuclear cells of Chinese nickel refinery workers with high exposures to nickel and control subjects. Cancer epidemiology, biomarkers & prevention.22(2):261-269, 2013.
  2. Xu, X., Deng, F., Guo, X., Lv, P., Zhong, M., Liu, C., Wang, A., Tzan, K., Jiang, S.Y., Lippmann, M., Rajagopalan, S., Qu, Q., Chen, L.-C., Sun, Q. Association of systemic inflammation with marked changes in particulate air pollution in Beijing in 2008.Toxicology Letter. 212(2):147-156, 2012.
  3. Arita, A; Shamy, MY; Chervona, Y; Clancy, HA; Sun, H; Hall, MN;Qu, Q; Gamble, MV; Costa, M.The effect of exposure to carcinogenic metals on histone tail modifications and gene expression in human subjects.Journal of trace elements in medicine & biology. 26(2-3):174-178, 2012.
  4. Arita A; Niu J; Qu Q; Zhao N; Ruan Y; Nadas A; Chervona Y; Wu F; Sun H; Hayes RB; Costa M.Global Levels of Histone Modifications in Peripheral Blood Mononuclear Cells of Subjects with Exposure to Nickel.Environmental health perspectives. 120(2):198-203, 2012.
  5. Liberda EN, Cuevas AK, Gillespie PA, Grunig G, Qu Q, Chen LC. Exposure to inhaled nickel nanoparticles causes a reduction in number and function of bone marrow endothelial progenitor cells.Inhal Toxicol. 22 (SUPPL. 2):95–99, 2010.
  6. Wang S, Prophete C, Soukup JM, Chen LC, Costa M, Ghio A, Qu Q, Cohen MD, Chen H. Roles of MAPK pathway activation during cytokine induction in BEAS-2B cells exposed to fine World Trade Center (WTC) dust.J Immunotoxicol. 7(4):298-307, 2010.
  7. Qu, S., Liberda, E.,Qu, Q., Chen, L-C. In Vitro assessment of the inflammatory response of respiratory endothelial cells exposed to particulate matter. J Toxicol. Environ. Health Part A.73:1113-1121, 2010.
  8. Schayer, S., Qu, Q., Wang, Y., Cohen, B.210Pb: A Predictive Biomarker of Retrospective Cigarette Smoke Exposure. Cancer Epidemiol Biomarkers Prev; 19(2):338–50, 2010.
  9. Schayer, S., Nowak, B., Wang, Y., Qu, Q., and Cohen, B.210Po and 210Pb activity in Chinese cigarettes. Health Phys.96(5):543-549, 2009.
  10. Qu, Q., Li, X., An, F., Jia, G., Liu, L., Watanabe-Meserve,H., Koenig, K., Cohen, B., Costa, M., Roy, N., Zhong, M., Chen, LC., Liu, S., Yan, L.Cr(VI) exposure and biomarkers: Cr in erythrocytes in relation to exposure and polymorphism of gene encoding anion transport proteins.Biomarkers13(5):467-477, 2008.
  11. Hu, Y., Li, G., Xue, X., Zhou, Z., Li, X., Fu, J., Cohen, B., Roy, N., Li, D., Sun, J., Nan, P., Tang, M-s.,Qu, Q.PAH-DNA adducts in a Chinese population: Relationship to PAH exposure, smoking, and polymorphisms of metabolic and DNA repair genes.Biomarkers13(1):27-40, 2008
  12. Ouyang, W., Hu, Y., Li, J., Ding, M., Lu, Y., Zhang, D., Yan, Y., Song, L.,Qu, Q., Desai, D., Amin, S., Huang C. Direct evidence for the critical role of NFAT3 in benzo[a]pyrene diol-epoxide-induced cell transformation through mediation of inflammatory cytokine TNF induction in mouse epidermal Cl41 cells.Carcinogenesis. 28(10): 2218-2226, 2007.
  13. Hu,Y., Zhou, Z., Xiaonan Xue, X., Li, X.,Fu, J., Cohen, B., Melikian, A., Desai, M., Tang, M-s., Huang, X., Nirmal Roy, N., Sun, J., Nan, P., andQu, Q.A Sensitive Biomarker of PAHs: Urinary 1-Hydroxyprene Glucuronide in Relation to Smoking and Low Ambient Levels of Exposure.Biomarkers114(2):306-318, 2006
  14. Yan Y, Li J, Ouyang W, Ma Q, Hu Y, Zhang D, Ding J, Qu Q, Subbaramaiah K, Huang C. NFAT3 is specifically required for TNF-{alpha}-induced cyclooxygenase-2 (COX-2) expression and transformation of Cl41 cells.J Cell Sci. 119(Pt 14):2985-94, 2006
  15. Qu, Q., Shore, R., Li, G., Su, L., Jin, X., Melikian, AA., Roy, N., Chen, LC., Wirgin, I., Cohen, B., Yin, S., Li, Y., and Mu, R. Biomarkers of benzene: urinary metabolites in relation to individual genotype and personal exposure.Chemico-Biological Interactions 153-154:85-95, 2005
  16. Rappaport, SM., Waidyanatha, S., Yeowell-O’Connell, K., Rothman, N., Smith, MT., Zhang, L.,Qu, Q., Shore, R., Li, G., and Yin, S.Protein adducts as biomarkers of human benzene metabolism. Chemico-Biological Interactions 153-154:103-109, 2005.
  17. Qu, Q; Hu, Y; Xue, X; Zhou, Z; Li, X; Fu, J; Cohen, B; Tang, E; Roy, N; Melikian, AA; Li, D."Validation of biomarkers in humans exposed to PAHs".Toxicology & applied pharmacology. 197:187, 2004
  18. Qu, QS., Shore, R., Li, G., Jin, X., Chen, LC., Cohen, B., Melikian, AA., Eastmond, D., Rappaport, S., Li, H., Rupa, D.,Waidyanatha,S., Yin, S., Yan, H., Meng, M., Winnik, W., Kwok, ESC., Li, Y., Mu, R., Xu, B., X., Zhang, Li, K.The validation and evaluation of biomarkers in humans exposed to benzene in China. HEI Research Report115, 2003
  19. Qu, QS., Cohen, B., Shore, R., Chen, LC., Li, G., Jin, X., Melikian, AA., Yin, S., Yan, H., Xu, B., Li, Y., Mu, R., Zhang, X., and Li, K.Benzene Exposure Measurement in Shoe and Glue Manufacturing:  A Study to Validate Biomarkers.Appl. Occup. Environ. Hygiene. 18:988-998, 2003
  20. Qu, QS., Shore, R., Li, G., Jin, X., Chen, LC, Cohen, B, Melikian, AA., Eastmond, D, Rappaport, SM, Yin, S, Li,H, Waidyanatha, S, Li, Y, Mu, R, Zhang, X, and Li, K. Hematological Changes Among Chinese Workers With a Broad Range of Benzene Exposures. AM. J. IND. MED. 42:275–285, 2002
  21. Melikian, AA., Qu, QS., Shore, R., Li,. G., Li, H., Jin, X., Cohen, B., Chen, LC., Li, Y., Yin, S., Mu, R., Zhang, X., Wang Y. Personal exposure to different levels of benzene and its relationships to the urinary metabolitesS-phenylmercapturic acid a Alpert, S.E., Walenga, R.W., Jaspers, I.,Qu, Q.S., and Chen, L.C. Ozone inactivates cyclooxygenase in human tracheal epithelial cells without altering PGHS-2 mRNA or protein. Am. J. Physiol. 272:L879-L887, 1997ndtrans,trans-muconic acid. J. Chromatography B, 778: 211–221, 2002
  22. Rappaport, SM, Waidyanatha, S., Qu, QS., Shore, R., Jin, X., Cohen, B., Chen, LC., Melikian, AA., Li, G., Yin, S., Yan, H., Xu, B., Mu, R., Li, Y., Zhang, X., and Li, K. Albumin Adducts of Benzene Oxide and 1,4-Benzoquinone as Measures of Human Benzene Metabolism. CANCER RES. 62:1330–1337, 2002.
  23. Qu, Q.S., Melikian, A.A., Li, G.L., Shore, R., Chen, L.C., Cohen, B., Yin, S.N., Kagan, M., Li, H., Meng, M., Jin, X., Winnik, W., Li, Y., Mu, R., Li, K. Validation of biomarkers in humans exposed to benzene: Urine metabolites.Am. J. Ind. Med. 37:522-531, 2000
  24. Chen, L.C., Su, W.C.,Qu, Q., Cheng, T.J., Chan, C.C., and Hwang, J.S. Composition of particulate matter as the determinant of cellular response. Proceedings of the 3rdColloquium on Particulate Air Pollution and Human Health, June 6-8, Durham, NC, 1999
  25. Alpert, S.E., Walenga, R.W., Jaspers, I., Qu, Q.S., and Chen, L.C. Ozone inactivates cyclooxygenase in human tracheal epithelial cells without altering PGHS-2 mRNA or protein. Am. J. Physiol. 272:L879-L887, 1997

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