Dr. Lada Zivkovic

Faculty of Pharmacy

University of Belgrade, Serbia

Assistant Professor for Biology and Human Genetics



2010 Ph.D., Biological Science Faculty of Biology University of Belgrade

2004 M.Sc., Biological Science, Faculty of Biology University of Belgrade

1996 B.Sc., The Faculty of Molecular Biology and Physiology University of Belgrade

Research Fields

Role of centromere and centromere associated proteins in Alzheimers Disease

Genetics of aging

Publications (selected)

  1. Vladan Bajic, Vesna Mandusic, Elka Stefanova, Ana Bozovic, Radoslav Davidovic, Lada Zivkovic, Andrea Cabarkapa, Biljana Spremo-Potparevic. Skewed X-Chromosome Inactivation in Women Affected by Alzheimer's Disease. J. Alzheimers Dis. J Alzheimers Dis 2014 Aug 26. Epub 2014 Aug 26.
  2. Plecas-Solarovic Bosiljka, Djelic Ninoslav, Bajic Vladan, Zivkovic Lada, Biljana Spremo-Potparevic. Cytogenetic aleterations in Peripheral Cells of Alzheimer'S Disease Patients.GENETIKA-BELGRADE, (2014), vol. 46 br. 1, str. 315-330.
  3. Ninoslav Djelić, Milena Radaković, Biljana Spremo-Potparević, Lada Zivković, Vladan Bajić, Jevrosima Stevanović, Zoran Stanimirović Evaluation of cytogenetic and DNA damage in human lymphocytes treated with adrenaline in vitro.Toxicol In Vitro Toxicol In Vitro 2014 Aug 27. Epub 2014 Aug 27.
  4. Cabarkapa A, Zivković L, Zukovec D, Djelić N, Bajić V, Dekanski D, Spremo-Potparević B.Protective effect of dry olive leaf extract in adrenaline induced DNA damage evaluated using in vitro comet assay with human peripheral leukocytes. Toxicol In Vitro. 2014.
  5. Milićević Z, Bajić V, Zivković L, Kasapović J, Andjelković U, Spremo-Potparević B. Identification of p53 and Its Isoforms in Human Breast Carcinoma Cells. ScientificWorld Journal. 2014. 5;2014:618698. doi: 10.1155/2014/618698.
  6. Zivković L, Spremo-Potparević B, Siedlak SL, Perry G, Plećaš-Solarović B, Milićević Z, Bajić VP. DNA Damage in Alzheimer Disease Lymphocytes and Its Relation to Premature Centromere Division. Neurodegener Dis.;12(3):156-63.
  7. Zivkovic Lada P, Bajic Vladan P, Zukovec Dijana, Cabarkapa Andrea, Spremo- Potparevic Biljana. Alterations of Acrocentric Chromosomes in Peripheral Blood Lymphocytes in Patients with Alzheimer'S Disease (Article) ARCHIVES OF BIOLOGICAL SCIENCES, (2013), vol. 65 br. 2, str. 439-445.
  8. Zivkovic Lada P, Djelic Ninoslav J, Bajic Vladan P, Bogavac-Stanojevic Natasa, Zukovec Dijana, Cabarkapa Andrea, Spremo-Potparevic Biljana. Evaluation of DNA Damage in the Lymphocytes of Young, Elderly and Alzheimer'S Disease Patients Treated with Beta- Estradiol in the Comet Assay . JOURNAL OF MEDICAL BIOCHEMISTRY, (2013), vol. 32 br. 3, str. 238-244.
  9. Bajic Vladan,; Spremo-Potparevic Biljana,; Vesna Mandusic,; Milicevic Zorana; Lada Zivkovic. Instability in X chromosome inactivation patterns in AMD: a new risk factor? Ophthalmol 2013; Vol. 2, No 3 Medical Hypothesis, Discovery &Innovation Ophthalmology Journal.
  10. V.P.Bajic, D.J Bonda, L. Zivkovic, Z. Milicevic,B.Plecas Solarevic, Xiongwei Zhu and B.Spremo Potparevic. The Role of centromere cohesion and associated proteins in Alzheimer's Disease: A relation to Aneuploidy? In. Aneuploidy'' Etiology, Disorders and Risk Factors, Editors: Salvatore de Rossi and Filippo Bianchi. Chapter IV, pp 77-90, ISBN:978-1-62100-070-9, 2012 Nova Science PubAlishers, INC. USA.
  11. B. Spremo-Potparević, L. Živković, B. Plećas-Solarović and V.P. Bajić. 2011. Chromosome instability in Alzheimer’s disease. Arch. Biol.Ssci., Belgrade, 63 (3), 603- 608.
  12. Bajić VP, Su B, Lee HG, Kudo W, Siedlak SL, Zivković L, Spremo-Potparević B, Djelic N, Milicevic Z, Singh AK, Fahmy LM, Wang X, Smith MA, Zhu X. 2011. Mislocalization of CDK11/PITSLRE, a regulator of the G2/M phase of the cell cycle, in Alzheimer disease. Cell Mol Biol Lett. 16(3):359-72.
  13. Lada Živković, Bosiljka Plećaš, Vladan Bajić, Ninoslav Đelić, Biljana Spremo-Potparević. 2011. Ispitivanje genetičke nestabilnosti leukocita periferne krvi pacijenata sa Alchajmerovom bolešću primenom Komet testa. Arh. Farm. vol. 61, br. 1, str. 28-41.
  14. L. Zivkovic , B. S. Potparevic , Bosiljka Plecas-Solarevic, Ninoslav Djelic, Gordana Ocic, Predrag Smiljkovic, Sandra Siedlak, M. A.Smith and Vladan Bajic. 2010. Premature Centromere Division of Metaphase Chromosomes in Peripheral Blood Limphocytes of Alzheimer’s Disease Patients: Relation to Gender and Age. J Geront A Biol Med Sci, J Gerontol A Biol Sci Med Sci. 65A(12):1269–1274.
  15. Vladan Bajic, L. Zivkovic , B. S. Potparevic , Sandra Siedlak, M. A.Smith. 2010. RAD 21 cohesion protein shows altered levels of expression in Swedish mutant phenotype of M17 neuroblastoma cells. PI-288. Alzheimer's & Dementia: The Journal of the Alzheimer's Association Vol. 6, Issue 4, Supplement, Page S257.
  16. Vladan Bajic, Zoran Stanimirovic, Jevrosima Stevanovic, Zorka Milicevic, Lada Zivkovic , Biljana Spremo- Potparevic, 2010. Effect of Paclitaxel alone and in combination with Cycloheximide on the Frequency of Premature Centromere Division in vitro. Arch of Biol Scienc. 62(1), 63-74.
  17. Bajic, V., Siedlak, S., Zivkovic, L., Spremo-Potparevic, B., Gemma Casadeus and Smith MA. 2009. The X-chromosome instability phenotype in Alzheimer’s disease: A clinical sign of accelerating aging? Medical Hypothesis,73(6):917-20.
  18. Bajic V, Stanimirovic Z, Stevanovic J, Spremo-Potparevic B, Zivkovic L, Milicevic Z. 2009.Cytogenetic effects of 8-Cl-cAMP on human and animal chromosomes. J BUON. 14(1):71-77.
  19. Bajic V., Spremo-Potparavic B., Milicevic Z., Djelic N. and Zivkovic L, 2008. A study on the genotoxic effects of 8-Cl-cAMP on human lymphocytes in vitro. Russian Journal of Genetics,44,No 5, 1-7.
  20. Biljana Spremo-Potparević, Lada Živković, Ninoslav Djelić and Vladan Bajić, 2008. Premature centromere division (PCD) of the X chromosome of cerebral cortex cells in Alzheimer disease patients. Journal of Neurochemistry, 106 (5):2218-23.
  21. Vladan P. Bajić, Biljana Spremo-Potparević, Lada Živković, Ninoslav Djelić, Mark A. Smith, 2008. Is the time dimension of the cell cycle re-entry in AD regulated by centromere cohesion dynamics? Biosciencel Hypothesis Vol 1, Issue 3. pp:156-161.
  22. Bajic V., Spremo-Potparavic B., Milicevic Z. and Zivkovic L. 2007. Deregulated sequential motion of centromeres induced by antitumor agnets may lead to genome instability in human peripheral blood lymphocytes. Journal of BUON 12: 77-83.
  23. Spremo-Potparević B., Živković L., Drakulić D., Bajić V., Djelić N. Premature centromere division (PCD) of the X chromosome as a bio-marker of the brain cells re-entry into the cell division cycle in Alzheimer's disease. In Frontiers in Alzheimer's Disease Research, Nova Science Publishers, Inc., New York, USA, Editor E.M.Welsh 2006, 163-177. ISSN 1-59454-929-X3.
  24. L. Zivkovic, B. Spremo-Potparevic, N. Djelic and V.Bajic, 2006: Analysis of premature centromere division (PCD) of the chromosome 18 in peripheral blood lymphocytes of Alzheimer’s disease patients. Mechanism of Ageing and Development, 127:892-896.
  25. Spremo-Potparevic B, Zivkovic L, Djelic N and Bajic V., 2004. Analysis of premature centromere division (PCD) of the X chromosome in Alzheimer patients through the cell cycle. Journal of Exper. Gerontology 39 : 849-854.

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Last Updated: 2014-09-22

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