Dr. J. Yuen-Shan Ho

The Hong Kong Polytechnic University, China

Assistant Professor



2005-2009 Ph.D., The University of Hong Kong, Neuroscience

Publications (selected)

  1. Ho YS, Yang XF, Yeung SC, Chiu K, Lau CF, Tsang AWT, Mak JCW and Chang RCC (2012) Cigarette smoking accelerated brain aging and induced pre-Alzheimer-like neuropathology in rats. PLoS ONE, 7, e36752.
  2. Ho YS, Yang X, Lau JC, Hung CH, Wuwongse S, Zhang Q, Wang J, Baum L, So KF, Chang RCC (2012) Endoplasmic reticulum stress induces tau pathology and forms a vicious cycle: Implication in Alzheimer’s disease pathogenesis. J. Alz. Dis., 28, 839-854.
  3. Ho YS*, Poon DCH Chan TF and Chang RCC (2012) From small to big molecules: how do we prevent and delay progression of aging-related neurodegeneration? Curr. Pharm. Design, 18, 15-26. (Co-correspondence author; Impact factor: 4.774; Rank of Journal: 22/249 (Top 8.8%) in the field of Pharmacology and Pharmacy)
  4. Yik SY, Yu MS, Ho YS, Lai SW, Cheung YT, So KF and Chang RCC (2012) Neuroprotective effects of minocycline on double-stranded RNA-induced neurotoxicity in cultured cortical neurons, Hong Kong Medical Journal, 18 No. 1 Supplement, 42-44.
  5. Ho YS*, So KF and Chang RCC (2011) Drug discovery from Chinese Medicine against neurodegeneration in dementia. Chin. Med., 6, 15. (Co-correspondence author; New Journal with pending impact factor)
  6. Ho YS, Hung CHL and Chang RCC (2011) Green tea and neurodegeneration in Alzheimer’s disease. In: Victor R. Preedy Ed. Tea in Health and Disease Prevention. Elsevier Publisher (Book Chapter). In press. (Co-correspondence author)
  7. Ho YS, Yu MS, Yang X, So KF, Yuen WH and Chang RCC (2010) Neuroprotective effects of polysaccharides from Wolfberry, the fruits of Lycium barbarum, aganist homocysteine-induced toxicity in rat cortical neurons. J. Alz. Dis., 19, 813-827. (Impact factor: 4.261; Rank of Journal: 58/237 (Top 24.5%) in the field of Neuroscience; citation index: 7).
  8. Chang RCC, Ho YS, Yu MS and So KF (2010) Medicinal and nutraceutical uses of wolfberry in preventing neurodegeneration in Alzheimer’s disease. In: Charles Ramassamy and Stéphane Bastianetto Eds. Recent Advances on Nutrition and Alzheimer’s disease. (Book Chapter). pp 169-185.
  9. Hung CHL, Ho YS and Chang RCC (2010) Modulations of mitochondrial calcium as a pharmacological target for Alzheimer’s disease. Ageing Res. Rev., 9, 447-456. (Impact factor: 9.0; Rank of Journal: 1/44 (Top: 2.3%) in the field of Geriatric & Gerontology).
  10. Ho YS, Yu MS, Yik SY, Lai CSW, So KF, Yuen WH and Chang RCC (2008) Lycium barbarum protects neurons against neurodegeneration in Alzheimer’s disease through multiple approaches. (Abstr.) 3rd International Symposium on Healthy Aging: Improving the Health of an Aging Population. P44.
  11. Chang RCC, Yu MS, Ho YS, Lai SW, Chiu K and So KF (2008) Polysaccharides from medicinal herbs as potential drug lead in Alzheimer’s disease. (Abstr.) Neurobiology of Aging, 29S, S4-S5.
  12. Chang RCC, Lai SW, Yu MS, Cheung YT and Ho YS (2007) The impact from understanding the biological mechanisms of neurodegeneration in Alzheimer’s disease to the development of neuroprotective agents. (Abstr.) Asian Journal of Gerontology & Geriatrics, 2 (1): 31.

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