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Dr. Sam M. Wiseman

University of British Columbia, Canada

Email: SMWiseman@providencehealth.bc.ca


1995 M.D., University of Manitoba, Medicine

1991 B.Sc. University of Winnipeg, Biology

Publications (selected)

  1. Chiu CG, Harrisson P, Filipenko D, Wiseman SM: Thyroid Invasion by Locally Advanced Esophageal Cancer Masquerading as Anaplastic Carcinoma. Thyroid (2008) 18(8):799-800.
  2. Kan M, Gill J, Wiseman SM: Colon and Rectal Cancer after Renal Transplantation: A Review. Expert Reviews of Anticancer Therapy (2008) 8(8):1339-1346.
  3. Goetz J G, Lajoie P, Wiseman SM, Nabi IR: Caveolin-1 In Tumor Progression: The Good, The Bad And The Ugly. Cancer Metastasis Reviews (2008) 27(4):715-35.
  4. Tee M, Vos P, Zetler P, Wiseman SM: Incidental Littoral Cell Angioma of the Spleen: Case Report. World Journal of Surgical Oncology (2008) 6:87-92.
  5. Wiseman SM, Melck A, Masoudi H, Ghaaidi F, Gown A, Jones S, Griffith O: Molecular Phenotyping of Thyroid Tumors Identifies a Marker Panel for Differentiated Thyroid Cancer Diagnosis. Annals of Surgical Oncology (2008) 15(10):2811-2826. This report is the most comprehensive protein expression profiling study of thyroid tumors and identifies a molecular marker panel that characterizes benign and malignant thyroid tumors.
  6. Swanson T, Nanthakumar S, Bugis S, Wiseman S: Extrathyroidal Anaplastic Transformation Case Report & Review. Cancer Therapy (2008) 6:491-494. A case report and review of extra-thyroidal thyroid tumor progression.
  7. Griffith OL, Chiu CG, Gown AM, Jones SJ, Wiseman SM: Biomarker Panel Diagnosis of Thyroid Cancer: A Critical Review. Expert Reviews of Anticancer Therapy (2008) 8(9):1399-413. A comprehensive review of biomarker panel diagnosis approaches to thyroid cancer.
  8. Joshi B, Strugnell S, Goetz J, Kojic LD, Cox ME, Wiseman SM, Nabi IR: Phosphocaveolin-1 regulates Rho/ROCK-dependent focal adhesion dynamics and tumor cell migration. Cancer Research (2008) 68(20):8210-8220.
  9. Kojic LD, Wiseman SM, Ghaidi F, Joshi B, Nedev H, Saragovi HU, Nabi IR: Raft-Dependent Endocytosis of Autocrine Motility Factor/Phosphoglucose Isomerase: A Drug Delivery Route for Tumor Cells. PLoS One (2008) 3(10):e3597. Epub Oct 31.
  10. Lim JP, Irvine R, Bugis S, Holmes D, Wiseman SM: Intact Parathyroid Hormone Level Measured One Hour After Completion or Total Thyroidectomy Predicts Symptomatic Hypocalcemia. American Journal of Surgery (2008) 197(5):648-654.
  11. Deen S, Grifith O, Masoudi H, Gown A, Jones S, Wiseman S: Anaplastic Thyroid Carcinoma Exhibits Intratumoral Molecular Homogeneity for a Therapeutic Target Panel.Anticancer Research (2009) 29(7):2437-44.
  12. Vu L, Ambrose D, Vos P, Tiwari P, Rosengarten M, Wiseman S: Evaluation of MRI in the Diagnosis of Appendicitis During Pregnancy. Journal of Surgical Research
  13. (2009) 156(1):145-149.
  14. Wiseman S, Levine D, Sexsmith G, Ling H: Aortopulmonary Window Parathyroid Adenoma. Journal of the American College of Surgeons (2009) 209(3):412.
  15. Levine DS, Belzberg AS, Wiseman SM: Hybrid SPECT/CT imaging for Primary Hyperparathyroidism: case reports and pictorial review. Clinical Nuclear Medicine (2009) 34(11):779-784.
  16. Johner A, Tiwari P, Zetler P, Wiseman SM: Abdominal Wall Desmoid Tumors Associated With Pregnancy: Current Concepts. Expert Rev Anticancer Therapy (2009) 9(11):1675-1682.
  17. Levine DS, Wiseman SM: Fusion imaging for parathyroid localization in primary hyperparathyroidism. Expert Reviews of Anticancer Therapy (2010) 10(3):353-363.
  18. Chiu CG, Griffith OL, Strugnell SS, Nabi IR, Gown A, Walker B, Wiseman SM: Diagnostic utility of galectin-3 in thyroid cancer. American Journal of Pathology (2010) 176(5):2067-2081.
  19. Swanson T, Chan S, Jones S, Bugis S, Irvine R, Belzberg A, Levine D, Wiseman SM:Determinants of Tc-99m Sestamibi SPECT Scan Sensitivity in Primary Hyperparathyroidism. American Journal of Surgery (2010) 199(5):614-620.
  20. Chiu CG, Masoudi H, Leung S, Voduc DK, Gilks B, Hunstman DG, Wiseman SM: HER-3 Over-Expression is Prognostic of Reduced Breast Cancer Survival: A Study of 4,046 Patients. Annals of Surgery (2010) 251(6):1107-1116.
  21. Melck AL, Wiseman SM: Harmonic Scalpel versus Conventional Hemostasis in Thyroid Surgery: a Meta-analysis of Randomized Clinical Trials. International Journal of Surgical Oncology 2010 (2010): 1-8.
  22. Kojic S, Strugnell SS, and Wiseman SM: Anaplastic Thyroid Cancer: A comprehensive review of novel therapy. Expert Reviews in Anti-Cancer Therapy. (2011) 11(3):387-402.
  23. Yao R, Chui C, Strugnell SS and Wiseman SM: Gender differences in thyroid cancer: a critical review. Expert Reviews of Endocrinology and Metabolism (2011) 6(2):215-243.
  24. Johner A, Griffith OL, Wood L, Piper H, Wilkins G, Walker B, Baliski C, Jones S and Wiseman SM: Detection and Management of Hypothyroidism Following Thyroid Lobectomy: Evaluation of a Clinical Algorithm. Epublished ahead of print in press Annals of Surgical Oncology. (2011) 18(9):2548-2554.
  25. Johner A, Faulds J, and Wiseman SM: Planned Ilioinguinal Nerve Excision For Prevention Of Chronic Pain After Inguinal Hernia Repair: A Meta-Analysis. Surgery (2011) 150(3):534-541
  26. Wiseman SM, Gown A, Walker B, Griffith O, Jones S: Immunophenotyping Of Thyroid Tumors Identifies Molecular Markers Altered During Transformation of Differentiated Into Anaplastic Carcinoma. American Journal of Surgery. (2011) 201(5):580-586.
  27. Chiu CG, Yao R, Chan SK, Strugnell SS, Walker B, Jones S, and Wiseman SM: Hemithyroidectomy is the Preferred Initial Surgical Approach for Indeterminant Thyroid Lesions. In press Canadian Journal of Surgery.
  28. Wiegand KC, Lee AF, Al-Agha OM, Chow C, Scott D, Steidl C, Wiseman SM. Gascoyne RD, Gilks B, Huntsman DG: Loss of BAF250a (ARID1A) is frequent in highgrade endometrial carcinomas. Journal of Pathology. (2011) 224(3):328-333
  29. Halwani Y, Nicolau-Toulouse V, Oakes J, Leipsic J, Geoffrion R and Wiseman SM: Transvaginal Strangulated Small Intestinal Hernia After Abdominal Sacrocolpopexy: Case Report And Literature Review. Hernia. (2011) July 15 Epublished ahead of print.
  30. Wiseman SM, Forrest JI, Chan JE, Zhang W, Hogg RS, Yip B, Lima V, Montaner JSG:Factors Predictive of 30 Day Post-Operative Mortality In HIV/AIDS Patients In The Era Of Highly Active Antiretroviral Therapy. Annals of Surgery. (2012) May 10 Epub ahead of print.
  31. Chiu CG, Chan SK, Fang ZA, Masoudi H, Wood-Baker R, Jones SJM, Laskin J,
  32. Wiseman SM. Loss of Beta-catenin Expression is Prognostic of Reduced Survival in
  33. Individuals Diagnosed with Resectable Non-small cell Lung Cancer. American Journal of Surgery. (2012) 203(5):654-659
  34. Kojic K, Kojik S, Wiseman SM: Differentiated Thyroid Cancers: A Comprehensive Review of Novel Targeted Therapies, Expert Reviews of Anticancer Therapy. (2012) 12 (3):345-357.