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Biography
Dr. Volodymyr Dvornyk
University of Hong Kong, China
 
Email: dvornyk@hku.hk
 
Qualifications
 
1992 Ph.D., Moscow Pedagogical State University, Moscow, Russia
1979-1984 M.S., Donetsk State University, Donetsk, Ukraine 
 
Publications (Selected)
  1. Sun L, Tan L, Yang F, Luo Y, Li X, Deng HW, Dvornyk V. 2012. Meta-analysis suggests that smoking is associated with earlier age at natural menopause.Menopause, 19(2): 126-132.
  2. Dvornyk V, Ul-Haq W. 2012. Genetics of age at menarche: a systematic review. Hum. Reprod. Update, 18(2): 198-210.
  3. Pan R, Liu YZ, Deng HW, Dvornyk V. 2012. Association analyses suggest the effects of RANK and RANKL on age at menarche in Chinese. Climacteric, 15(1): 75-81.
  4. Lu Y, Liu YZ, Liu PY, Dvornyk V, Deng HW. 2011. A bootstrap-based regression method for comprehensive discovery of differential gene expressions: the application to osteoporosis studies. Eur J Med Genet., 54(6): e560-e564.
  5. Lu Y, Liu P, Recker RR, Deng HW, Dvornyk V. 2010. TNFRSF11A and TNFSF11 are associated with age at menarche and natural menopause in white women. Menopause, 17(5): 1048-1054.
  6. Liu P, Lu Y, Recker RR, Deng HW, Dvornyk V. 2010. Association analyses suggest multiple interaction effects of the methylenetetrahydrofolate reductase polymorphisms on timing of menarche and natural menopause in whites. Menopause, 17(1): 185-190.
  7. Liu P, Lu Y, Recker RR, Deng HW, Dvornyk V. 2010. ALOX12 gene is associated with the onset of natural menopause in white women. Menopause, 17(1): 152-156.
  8. He L, Recker RR, Deng HW, Dvornyk V. 2009. A polymorphism of the APOE gene is associated with age at natural menopause in Caucasian females. Maturitas, 62(1): 37-41.
  9. Pei YF, Zhang L, Deng HW, Dvornyk V. 2008. Association of the CYP17 MspA1 polymorphism with age at menarche: a meta-analysis. Dis. Markers, 25(2): 87-95.
  10. Dvornyk V, Liu YZ, Lu Y, Shen H, Lappe J, Lei SF, Recker RR, Deng HW. 2007. Effect of menopause on gene expression profiles of circulating monocytes: a pilot in vivo microarray study. J. Genet. Genomics, 34(11): 974-983.
  11. Dvornyk V, Long JR, Liu PY, Shen H, Recker RR, Deng HW. 2006. Polymorphisms of the vitamin D receptor gene predict the onset of surgical menopause in Caucasian females. Gynecol. Endocrinol., 22(10): 552-556.
  12. Wang YB, Lei SF, Dvornyk V, Sun X, Jiang DK, Li MX, Deng HW. 2006. The genetic, environmental and phenotypic correlations of bone phenotypes at the spine and hip in Chinese. Ann. Hum. Biol., 33(4): 500-509.
  13. Liu YZ, Guo YF, Xiao P, Xiong DH, Zhao LJ, Shen H, Liu YJ, Dvornyk V, Long JR, Deng HY, Li JL, Deng HW. 2006. Epistasis between loci on chromosomes 2 and 6 influences human height. J. Clin. Endocrinol. Metab., 91(10): 3821-3825.
  14. Dvornyk V, Long JR, Zhao LJ, Shen H, Recker RR, Deng HW. 2006. Predictive factors for age at menopause in Caucasian females. Maturitas, 54(1): 19-26.
  15. Liu YZ, Xiao P, Guo YF, Xiong DH, Zhao LJ, Shen H, Liu YJ, Dvornyk V, Long JR, Deng HY, Li JL, Recker RR, Deng HW. 2006. Genetic linkage of human height is confirmed to 9q22 and Xq24. Hum. Genet., 119(3): 295-304.
  16. Deng FY, Lei SF, Li MX, Jiang C, Dvornyk V, Deng HW. 2006. Genetic determination and correlation of body mass index and bone mineral density at the spine and hip in Chinese Han ethnicity. Osteoporos. Int., 17(1): 119-124.
  17. Lei SF, Wu S, Dvornyk V, Deng HW. 2005. Two strategies to identify genes underlying complex diseases. Curr. Genomics, 6(7): 551-561.
  18. Shen H, Long JR, Xiong DH, Liu YJ, Liu YZ, Xiao P, Zhao LJ, Dvornyk V, Zhang YY, Rocha-Sanchez S, Liu PY, Li JL, Deng HW. 2005. Mapping quantitative trait loci for cross-sectional geometry at femoral neck. J. Bone Miner. Res., 20(11): 1973-1982.
  19. Long JR, Xu H, Zhao LJ, Liu PY, Shen H, Liu YJ, Xiong DH, Xiao P, Liu YZ, Dvornyk V, Li JL, Recker RR, Deng HW. 2005. The estrogen receptor α gene is linked and/or associated with age of menarche in different ethnic groups. J. Med. Genet., 42(10): 796-800.
  20. Zhang YY, Liu PY, Lu Y, Davies KM, Dvornyk V, Recker RR, Deng HW. 2005. Race and sex differences and contribution of height: a study on bone size in healthy Caucasians and Chinese.  Am. J. Hum. Biol., 17(5): 568-575.
  21. Yang YJ, Dvornyk V, Jian WX, Xiao SM, Deng HW. 2005. Genetic and environmental correlations between bone phenotypes and anthropometric indices in Chinese. Osteoporos. Int., 16(9): 1134-1140.
  22. Liu YZ, Dvornyk V, Lu Y, Shen H, Lappe J, Recker RR, Deng HW. 2005. A novel pathophysiological mechanism for osteoporosis suggested by an in vivo gene expression study of circulating monocytes. J. Biol. Chem., 280(32): 29011-29016.
  23. Dvornyk V, Liu PY, Long JR, Zhang YY, Lei SF, Recker RR, Deng HW. 2005. Contribution of genotype and ethnicity to bone mineral density variation in Caucasians and Chinese: a test for five candidate genes for bone mass. Chin. Med. J. (Engl.), 118(15): 1235-1244.
  24. Lei SF, Deng FY, Dvornyk V, Liu MY, Xiao SM, Jiang DK, Deng HW. 2005. The (GT)n polymorphism and haplotype in the COL1A2 gene, but not the (AAAG)n polymorphism in the PTHR1 gene, are associated with bone mineral density in Chinese. Hum. Genet., 116(3): 200-207.
  25. Long JR, Liu PY, Lu Y, Xiong DH, Zhang YY, Dvornyk V, Elze L, Recker RR, Deng HW. 2005. Tests of linkage and/or association of TGF-β1 and COL1A1 genes with peak bone mineral density. Osteoporos. Int., 16(1): 86-92.
  26. Liu YZ, Xu FH, Shen H, Liu YJ, Zhao LJ, Long JR, Zhang YY, Xiao P, Xiong DH, Dvornyk V, Li JL, Conway T, Davies KM, Recker RR, Deng HW. 2004. Genetic dissection of human stature in a large sample of multiplex pedigrees. Ann. Hum. Genet., 68(5): 472-488.
  27. Huang QY, Xu FH, Shen H, Zhao LJ, Deng HY, Liu YJ, Dvornyk V, Conway T, Davies KM, Li JL, Liu YZ, Recker RR, Deng HW. 2004. A second stage genome scan for QTLs influencing BMD variation. Calcif. Tissue Int., 75(2): 138-143.
  28. Shen H, Zhang YY, Long JR, Xu FH, Liu YZ, Xiao P, Zhao LJ, Xiong DH, Liu YJ, Dvornyk V, Rocha-Sanchez S, Liu PY, Li JL, Conway T, Davies KM, Recker RR, Deng HW. 2004. A genomewide linkage scan for bone mineral density in an extended sample: evidence for linkage on 11q23 and Xq27. J. Med. Genet., 41(10): 743-751.
  29. Xu FH, Liu YJ, Deng HY, Huang QY, Zhao LJ, Shen H, Liu YZ, Dvornyk V, Conway T, Li JL, Davies KM, Recker RR, Deng HW. 2004. A follow-up linkage study for bone size variation in an extended sample. Bone, 35(3): 777-784.
  30. Long JR, Zhao LJ, Liu PY, Lu Y, Dvornyk V, Shen H, Liu YJ, Zhang YY, Xiong DH, Xiao P, Deng HW. 2004. Patterns of linkage disequilibrium and haplotype distribution in disease candidate genes. BMC Genet., 5:11.
  31. Dvornyk V, Xiao P, Liu YJ, Shen H, Deng HW. 2004. Systemic approach to the study of complex bone disorders at the whole-genome level. Curr. Genomics, 5(2): 93-108.
  32. Long JR, Zhang YY, Liu PY, Liu YJ, Shen H, Dvornyk V, Zhao LJ, Deng HW. 2004. Association of estrogen receptor a and vitamin D receptor gene polymorphisms with bone mineral density in Chinese males. Calcif. Tissue Int., 74(3): 270-276.
  33. Dvornyk V, Long JR, Xiong DH, Liu PY, Shen H, Zhang YY, Liu YJ, Zhao LJ, Rocha-Sanchez SMS, Xiao P, Recker RR, Deng HW. 2004. Current limitations of SNP data from the public domain for studies of complex disorders: a test for ten candidate genes for obesity and osteoporosis. BMC Genet., 5:4.
  34. Liu YJ, Xu FH, Shen H, Liu YZ, Deng HY, Zhao LJ, Huang QY, Dvornyk V, Conway T, Davies KM, Li JL, Recker RR, Deng HW. 2004. A follow-up linkage study for quantitative trait loci contributing to obesity-related phenotypes. J. Clin. Endocrinol. Metab., 89(2): 875-882.
  35. Lei SF, Deng FY, Li MX, Dvornyk V, Deng HW. 2004. Bone mineral density in elderly Chinese: Effects of age, gender, weight, height and body mass index. J. Bone Miner. Metab., 22(1): 71-78.
  36. Liu YZ, Xu FH, Shen H, Deng HY, Liu YJ, Zhao LJ, Dvornyk V, Conway T, Li JL, Huang QY, Davies KM, Recker RR, Deng HW. 2003. A confirmation linkage study in support of the X chromosome harboring a QTL underlying human height variation. J. Med. Genet., 40(11): 825-831.
  37. Long JR, Liu PY, Zhang YY, Shen H, Liu YJ, Dvornyk V, Deng HW. 2003. Interaction effects between the estrogen receptor a gene, the vitamin D receptor gene, age and sex on bone mineral density in Chinese. J. Hum. Genet., 48(10): 514-519.
  38. Dvornyk V, Liu XH, Shen H, Lei SF, Zhao L, Huang QR, Qin Y, Jiang DK, Long J, Zhang Y, Gong G, Recker RR, Deng HW. 2003. Differentiation of Caucasians and Asians at bone mass candidate genes: implication for ethnic difference of bone mass. Ann. Hum. Genet., 67(3): 216-227.
  39. Dvornyk V, Recker R, Deng HW. 2003. Gene expression studies of osteoporosis: implications for microarray research. Osteoporos. Int., 14(6): 451-461.
  40. Lei SF, Deng FY, Liu XH, Huang QR, Qin Y, Zhou Q, Jiang DK, Li YM, Mo XY, Liu MY, Chen XD, Wu XS, Shen H, Dvornyk V, Zhao L, Recker RR, Deng HW. 2003. Polymorphisms of four bone mineral density candidate genes in Chinese populations and the comparison with other populations of different ethnicity. J. Bone Miner. Metab., 21(1): 34-42.