Prof. Kota V Ramana

Medical Branch

University of Texas, USA

Email: kvramana@utmb.edu

Qualifications

1998  Ph.D., Biochemistry, Postgraduate Institute of Medical Education and Research

Publications (Selected)

1. Yadav UCS, Shoeb M, Srivastava SK, Ramana KV*. Amelioration of Experimental Autoimmune Uveoretinitis by Aldose Reductase Inhibition in Lewis Rats.Invest Ophthalmol Vis Sci. 52(11): 8033-41, 2011.
2. Yadav UCS, Shoeb M, Srivastava SK and Ramana KV*. Aldose reductase deficiency protects from autoimmune- and endotoxin–induced uveitis in mice.Invest Ophthalmol Vis Sci52(11): 8076-85,2011.
3. Kalariya NM, Reddy ABM, Van Kuijk FGJM and Ramana KV*. Preventive Effects of Ethyl Pyruvate on Endotoxin-induced Uveitis in Rats. Invest Ophthalmol Vis Sci. 52(8): 5144-52; 2011.
4. Tammali R, Saxena A, Srivastava SK and Ramana KV*.Aldose reductase inhibition prevents hypoxia-induced increase in HIF-1 and VEGF by regulating the 26S proteasome mediated protein degradation in human colon cancer cells. J. Biol. Chem. 286(27): 24089-100, 2011.
5. Kalariya NM, Ramana KV Srivastava SK and Van Kuijk FGJM. Post-translational protein modification bycarotenoidcleavage products. Biofactors. 37: 104-116, 2011.
6. Yadav UC, Kalariya NM and Ramana KV*.Emerging role of antioxidants in the prevention of uveitis complications. Curr Med Chem. 18: 931-942, 2011.
7. Srivastava SK, Saxena A, Mishra RK, Yadav UCS, Tammali R, Aramati B, Ansari N, Bhatnagar A, Petrash MJ, Srivastava S and Ramana KV*. Aldose reductase inhibition suppresses oxidative stress-induced inflammatory disorders. Chem Biol Inter, 191: 330-338, 2011.
8. Reddy ABM, Srivastava S, Tammali R, Srivastava SK and Ramana KV*.Aldose reductase deficiency protects from sugar-induced lens opacification in rats. Chem Biol Inter, 191: 340-346, 2011.
9. Yadav UC,Sriavstava SKandRamana KV*. Inhibition of Aldose Reductase Attenuates Endotoxin Signals in Human Non-pigmented Ciliary Epithelial Cells. Exp. Eye Res.90: 555-563, 2010.
10. Ramana KV*. Tumor necrosis factor-alpha converting enzyme: Implications for ocular inflammatory diseases.Int J Biochem Cell Biol. 42: 1076-9, 2010.
11. Kalariya NM, Shoeb M, Reddy AB, Zhang M, van Kuijk FJ, Ramana KV. Plant Sterol Guggulsterone Prevents Endotoxin-induced Uveitis in Rats. Invest Ophthalmol Vis Sci.51(10): 5105-13,2010.
12. Yadav UC, Srivastava SK, Ramana KV*.Understanding the role of aldose reductase in ocular inflammation. Curr Mol Med. 10: 540-9, 2010.
13. Kalariya NM, Wills NK,Ramana KV,Srivastava SK, van Kuijk FJ. Cadmium‐induced apoptotic death of human retinal pigment epithelial cells is mediated by MAPK pathway. Exp. Eye Res. 89: 494-502, 2009.
14. Xiao T, Shoeb M, Siddiqui MS, Zhang M, Ramana KV, Srivastava SK, Vasiliou V, Ansari NH. Molecular cloning and oxidative modification of human lens ALDH1A1: implication in impaired detoxification of lipid aldehydes. J Toxicol Environ Health A. 72: 577-84, 2009.
15. Yadav UC, Igani HF, VanKuijk FJ, Srivastava SK and Ramana KV*. Aldose Reductase Inhibition Prevents Posterior Capsular Opacification in Porcine Eye Capsular Bag Model. Invest Ophthalmol Vis Sci. 50: 752-759, 2009.
16. Yadav UC, Subramanyam S, Ramana KV*. Prevention of endotoxin-induced uveitis in rats by benfotiamine, a lipophilic analogue of vitamin B1. Invest Ophthalmol Vis Sci. 50: 2276-82, 2009.
17. Kalariya NM,Ramana KV,Srivastava SK, van Kuijk FJ. Genotoxic Effects of Carotenoid Derived Aldehydes in Human Retinal Pigment Epithelial Cells. Cur Eye Res. 34: 737-747, 2009.
18. Srivastava SK and Ramana KV*.Focus on molecules: Nuclear Factor-kappaB. Exp Eye Res. 88: 1-2, 2009.
19. Yadav UC, Srivastava SK, Ramana KV*.Aldose reductase inhibition prevents endotoxin-induced uveitis in rats. Invest Ophthalmol Vis Sci. 48: 4634-42,2007.
20. Kalariya NM, Ramana KV, Srivastava SK, van Kuijk FJ. Carotenoid derived aldehydes-induced oxidative stress causes apoptotic cell death in human retinal pigment epithelial cells. Exp Eye Res. 86: 70-80, 2008.
21. Pladzyk, A., Aramati, B.M.R., Yada, U.C.S., Tammali, R., Ramana, K.V. and Srivastava, S.K.  Inhibition of aldose reductase prevents lipopolysaccharide-induced inflammatory response in human lens epithelial cells. Invest. Opthalmol. & Vis. Sci. 47: 5395-5403, 2006.
22. Srivatava, S., Tammali, R., Chandra, D., Greer, D.A., Ramana, K.V. and Srivastava, SK.Regulation of lens aldose reductase activity by nitric oxide. Exp. Eye. Res. 81: 664-672, 2005.

Profile Details

https://bmb.utmb.edu/bios/ramana