Prof. Chris Bystroff
Rensselaer Polytechnic Institute, USA
Email: bystrc@rpi.edu
Qualifications
1988 Ph.D., UCSD, La Jolla, USA
1985 M.Sc., UCSD, La Jolla, USA
1983 B.A., Carleton College, USA
Publications (Selected)
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Ramakrishnan V, Srinivasan S, Salem SM, Zaki MJ , Matthews
SJ, Colon W, & Bystroff C. (2011) GeoFold: Topology-based protein unfolding
pathways capture the effects of engineered disulfides on kinetic stability. Proteins (e-pub)
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Paredes DI, Watters KE, Pitman DJ, Bystroff C, &
Dordick JS (2011) Comparative Void-VolumeAnalysis of Psychrophilic and
Mesophilic Enzymes: Structural bioinformatics of psychrophilic enzymes reveals
sources of core flexibility BMC Structural Biology 11(1):42.
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Huang Y-M, Nayak S, Bystroff C. (2011) Quantitative in vivo solubility and reconstitution of truncated circular
permutants of green fluorescent protein. Protein Science20(11), 1771–1940.
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Buck PM & Bystroff C (2011) Constraining Local
Structure Using Rigid Body Dynamics Can Speed Up Folding By Promoting
Structural Polarization Of The Folding Pathway Protein Science 20(6):959-969
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Salem SM, Zaki MJ, Bystroff C. (2010) FlexSnap: Flexible
Non-Sequential Protein StructureAlignment. Algorithms for Molecular Biology Jan 4;5(1):12.
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Reeder PJ, Huang Y-M, Dordick JS & Bystroff C. (2010) A
Rewired Green Fluorescent Protein:Folding and Function in a Nonsequential,
Noncircular GFP Permutant. Biochemistry49(51),10773-10779.
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Cole B & Bystroff C. (2009) Alpha helical crossovers
favor right-handed supersecondary structures by a kinetic trapping mechanism.
The phone cord effect in protein folding.Protein Science 18(8) 1602 - 1608
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Salem, S., Zaki, M.J., Bystroff, C. (2009) Iterative
non-sequential protein structural alignment. JBioinform Comput Biol 7(3):571-96
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Huang Y-M & Bystroff C. (2009). Specific complementation
and reconstitution of flourescencefrom a circularly permuted,
truncated green fluoresent protein. Biochemistry48(5):929-40. abstract
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Buck P. & Bystroff C. (2008) Simulating protein folding
initiation sites using an alpha-carbononly knowledge-based force field. Proteins, Structure, Function and Bioinformatics 76(2):331-342.
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Bystroff C. & Webb-Robertson, B.J. (2008) Pairwise
covariance adds little to secondary structureprediction but improves the
prediction of non-canonical local structure. BMC Bioinformatics 9:429 (10
October 2008)
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Shentu, Z., al Hassan M., Bystroff C., Zaki, M. (2008).
Context Shapes: EfficientComplementary Shape Matching for Protein-Protein
Docking. Proteins. 70(3):1056-1073
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Shinde A., Bystroff C. Wang C., Vincent PA, Hynes RO, van
de Water, L. (2008). EIIIA (ED-A), the alternatively spliced segment of fibronectin exhibits cryptic cell
adhesive activity to integrin α9β1. J Biol Chem. 283(5):2858-70
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Xia K, Manning M, Hesham H, Lin Q, Bystroff C & Colon
W. (2007) Identifying theSubproteome of Kinetically Stable Proteins Via
Diagonal 2D SDS-PAGE. Proc Nat Acad SciU S A. 104(44):17329-34
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Protein Structure Prediction. Series: Methods in Molecular
Biology , Vol. 413. Zaki, Mohammed;Bystroff, Christopher (Eds.) 2nd ed., 2007
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Bystroff C. & Krogh A. (2007). Hidden Markov Models for
Protein Features. Chapter 13 of “Protein Structure Prediction, Methods and Protocols,
2nd Ed” (Zaki M, Bystroff C, eds.) Humana Press.
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Yuan X & Bystroff C. (2006). Protein Contact Map
Prediction. Chapter 9 of “ComputationalMethods for Protein Structure Prediction
and Modeling” (Ying Xu, Dong Xu and Jie Liang, eds.) Springer-Verlag, Heidelberg.
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Huang Y-M & Bystroff C. (2006). Improved pairwise
alignment of proteins in the Twilight Zoneusing local structure predictions.
Bioinformatics 22(4):413-420.
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Yuan X & Bystroff C. (2005). Non-sequential
Structure-based Alignments Reveal Topology-independent Core Packing
Arrangements in Proteins. Bioinformatics 27(7):1010-1019.
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Hou Y, Hsu W, Lee ML & Bystroff C. (2004). Remote
Homology Detection Using LocalSequence-structure Correlations. Proteins,
Structure, Function and Bioinformatics 57(3):518-30.
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Zaki MJ, Nadimpally V, Bardhan D, & Bystroff C. (2004).
Predicting Protein Folding Pathways. Bioinformatics 20 Suppl. 1, i387-i393.
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Bystroff C, Shao Y & Yuan X. (2004). Five heirarchical
levels of sequence-structure correlation in proteins. Applied Bioinformatics
3(2):97-104.
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Bystroff C & Shao Y. (2004). Modeling Protein Folding
Pathways. Practical Bioinformatics(Bujnicki, J. M., Ed.), 97-122,
Springer-Verlag, Heidelberg.
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Shao Y & Bystroff C. (2003). Predicting inter-residue
contacts using templates and pathways. Proteins, Structure, Function and
Genetics 53, 497-502.