Prof.
Daniela Quaglino
University
of Modena and Reggio Emilia, Italy
Email:
daniela.quaglino@unimore.it
Qualifications
1992 Ph.D., University of Bologna, Italy
1984 B.Sc., University of Modena, Italy
Publications
(Selected)
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Quaglino
D., Boraldi F., Barbieri D., Croce R., Tiozzo R., Pasquali Ronchetti I.
Abnormal phenotype of in vitro dermal fibroblasts from patients with
pseudoxanthoma elasticum (PXE). Biochim.Biophys. Acta, 1501: 51-62, 2000
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Le
Saux O., Urban Z., Tschuch C., Csizar K., Bacchelli B., Quaglino D., Pasquali
Ronchetti I., Pope FM., Richards A., Terry S., Bercovitch L., De Paepe A., Boyd
CD. Mutations in a gene encoding an ABC transporter (ABCC6) cause
Pseudoxanthoma elasticum. Nature Genetics, 25:223-227, 2000
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Capri
M., Quaglino D., Verzella G., Monti D., Bonafe M., Cossarizza A., Troiano
L.,.Zecca L., Pasquali Ronchetti I., Franceschi C. A cytofluorimetric study of
T lymphocyte subsets in rat lymphoid tissues (thymus, lymph nodes) and
peripheral blood: A continuous remodelling during the first year of life. Exp.
Gerontol., 35: 613-625, 2000
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Quaglino
D., Capri M., Pasquali Ronchetti I. Modulation of cell death in the rat thymus.
Light and electron microscopic investigations. Ann.N.Y.Acad. Sci.USA,
926:79-82, 2000
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Quaglino
D., Pasquali Ronchetti I. Cell death in the rat thymus: a minireview. Apoptosis
6: 389-401, 2001
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Baritussio
A., Marzini S., Agostani M., Alberti A., Cimenti C., Bruttomesso D., Manzato
E., Quaglino D., Pettenazzo A. Amiodarone inhibits lung degradation of SP-A and
perturbs the distribution of lysosomal enzymes. Am.J. Physiol. 281:
L1189-99,2001.
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Zhu
Y, Lin L, Kim S, Quaglino D., Lockshin RA, Zakeri Z. Cyclin dependent kinase 5
and its interacting proteins in cell death induced in vivo by cyclophosphamide
in developing mouse embryos. Cell Death Differ. 9:421-30, 2002
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Boraldi
F., Bini L., Liberatori S., Armini A., Pallini V., Tiozzo R.,
Pasquali-Ronchetti-I., Quaglino D. Normal human dermal fibroblasts: Proteomic
analysis of cell layer and culture medium. Electrophoresis, 24: 1292-1310, 2003
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Boraldi
F., Bini L., Liberatori S., Armini A., Pallini V., Tiozzo R.,
Pasquali-Ronchetti-I., Quaglino D. Proteome analysis of dermal fibroblasts
cultured in vitro from human healthy subjects of different ages. Proteomics, 3:
917-929, 2003
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Boraldi
F., Quaglino D., Croce M.A., Garcia Fernandez MI., Tiozzo R., Gheduzzi D.,
Bacchelli B., Pasquali Ronchetti I. Multidrug resistance protein-6 (MRP6) in
human dermal fibroblasts. Comparison between cells from normal subjects and
from Pseudoxanthoma elasticum patients Matrix Biol. 22:491-500, 2003
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Quaglino
D., Ha HR., Duner E., Bruttomesso D., Bigler L., Follath F., Reali G.,
Pettenazzo A., Baritussio A. Effects of metabolites and analogues of amiodarone
on alveolar macrophages: structure-activity relationship. Am J Physiol Lung
Cell Mol Physiol. 287:L438-47, 2004
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Quaglino
D., Boraldi F., Bini L., Volpi. N. The protein profile of fibroblasts: the role
of proteomics. Current Proteomics, 1: 167-178, 2004
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Gheduzzi
D., Guidetti R., Anzivino C., Tarugi P., Di Leo E., Quaglino D., Pasquali
Ronchetti I. ABCC6 mutations in Italian families affected by pseudoxanthoma
elasticum (PXE). Hum Mutat. 24: 438-439, 2004 and #775, pp 1-10 online, 2004
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Tamburro
AM, Pepe A, Bochicchio B, Quaglino D, Pasquali-Ronchetti I.Supramolecular
amyloid-like assembly of the polypeptide sequence coded by exon 30 of human
tropoelastin. J Biol Chem. 280:2682-90, 2005
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Gheduzzi
D, Guerra D, Bochicchio B, Pepe A, Tamburro AM, Quaglino D, Mithieux S, Weiss
AS, Pasquali Ronchetti I.Heparan sulphate interacts with tropoelastin, with
some tropoelastin peptides and is present in human dermis elastic fibers.
Matrix Biol. 24:15-25, 2005
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Quaglino
D., Sartor L., Garbisa, S., Boraldi F., Croce A., Passi A., De Luca G., Tiozzo
R., Pasquali-Ronchetti I. Dermal fibroblasts from Pseudoxanthoma elasticum
patients have raised MMP-2 degradative potential. Biochim. Biophys. Acta, 1741:
42-47, 2005
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Pepe
A, Guerra D, Bochicchio B, Quaglino D, Gheduzzi D, Pasquali Ronchetti I,
Tamburro AM. Dissection of human tropoelastin: Supramolecular organization of
polypeptide sequences coded by particular exons.Matrix Biol. 24:96-109, 2005.
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Pasquali
Ronchetti I., Gracia-Fernandez MI., Boraldi F., Quaglino D., Ghedizzi D.,
Paolinelli DeVincenzi C., Tiozzo R., Bergamini S., Ceccarelli D., Muscatello U.
Oxidative stress in fibroblsdtas from patients with pseudoxanthoma elasticum:
possibile role in the pathogenesis of clinical manifestations. J. Pathol., 208:
54-61, 2006
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Gheduzzi
D, Boraldi F, Annovi G, DeVincenzi CP, Schurgers LJ, Vermeer C, Quaglino D,
Pasquali-Ronchetti I. Matrix Gla protein is involved in elastic fiber
calcification in the dermis of pseudoxanthoma elasticum patients. Lab Invest.
87:998-1008, 2007
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Boraldi
F, Annovi G, Carraro F, Naldini A, Tiozzo R, Sommer P, Quaglino D. Hypoxia
influences the cellular cross-talk of human dermal fibroblasts. A proteomic
approach. Biochim Biophys Acta. 1774:1402-13, 2007
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Boraldi
F. Annovi G., Paolinelli-Devincenzi C., Tiozzo R., Quaglino D. The effect of
serum withdrawal on the protein profile of quiescent human dermal fibroblasts
in primary cell culture. Proteomics 8:66-82, 2008
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Pezet
M, Jacob MP, Escoubet B, Gheduzzi D, Tillet E, Perret P, Huber P, Quaglino D,
Vranckx R, Li DY, Starcher B, Boyle WA, Mecham RP, Faury G. Elastin Haploinsufficiency
Induces Alternative Aging Processes in the Aorta. Rejuvenation Res. 11: 97-112,
2008
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Pepe
A., Flamis R., Guerra D., Quaglino D., Bochicchio B., Pasquali-Ronchetti I.,
Tamburo AM. Exon 26-coded polipeptide: an isolated hydrophobic domain of human
tropoelastin able to self-assemble in vitro. Matrix Biology, 27:441-50,2008
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Garcia-Fernandez
MI, Gheduzzi D, Boraldi F, Paolinelli CD, Sanchez P, Valdivielso P, Morilla MJ,
Quaglino D, Guerra D, Casolari S, Bercovitch L, Pasquali-Ronchetti I. Parameters
of oxidative stress are present in the circulation of PXE patients.Biochim
Biophys Acta. 1782:474-81, 2008
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Boraldi
F., Annovi G., Guerra D., Paolinelli DeVincenzi C., Garcia-Fernandez MI.,
Panico F., De Santis G., Tiozzo R., Ronchetti I.Quaglino D. Fibroblast protein
profile analysis highlights the role of oxidative stress and vitamin-K
recycling in the pathogenesis of Pseudoxanthoma elasticum.
Proteomics-Clin.Appl., 3: 1-15 2009