Prof. Ramesh C.
Gupta
Toxicology
Department,
Murray
State University, USA
Professor
Email:
rgupta@murraystate.edu
Qualifications
1977
Ph.D., Punjab Agricultural University, Veterinary Sciences
1973
M.Sc., GB Pant University of Agriculture and Technology, Veterinary Medicine
1971
DVM, GB Pant University of Agriculture and Technology, Veterinary Medicine
Publications
(Selected)
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Litchfield,
H., Gupta, R.C., Doss, R.B., Bland, S.D., and Canerdy, T.D. Safety evaluation
of permethrin and indoxacarb in dogs topically exposed to Activyl tick plus. J.
Vet. Sci. Technol. 6(2): 1-9 (2015).
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May,
K., Gupta, R.C., Miller, J., Goad, J.T., Lasher, M.A., Conway, R., Canerdy,
T.D., Kalidindi, S.R. Therapeutic efficacy and safety evaluation of a novel
chromium supplement (Crominex+3) in moderately arthritic horses. J. Vet. Sci.
Res. 2(1):1-10.
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Nichols,
H., Gupta, R.C., Doss, R.B., Bland, S.D., Canerdy, T.D., and Zieren, J.:
Residue of fipronil, s-methoprene, and amitraz in dog blood and in gloves from
topical application Certifect application: Toxicity and safety considerations.
J. Vet. Sci. Res. 1:1-9 (2-14).
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Bland,
S.D., Gupta, R.C., Lasher, M.A., Canerdy, T.D.: Safety assessment of
etofenprox, s-methoprene, and piperonyl butoxide in dogs topically exposed to
Bio Spot defense. J. Vet. Sci. Technol. 4(6): 1-7 (2013).
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Lawley,
S., Gupta, R.C., Goad, J.T., Canerdy, T.D., Kalidindi, S.R.: Anti-inflammatory
and anti-arthritic efficacy and safety of purified Shilajit in moderately
arthritic dogs. J. Vet. Sci. Anim. Husb. 1(3):1-6 (2013).
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Fleck,
A., Gupta, R.C., Goad, J.T., Lasher, M.A., Canerdy, T.D.: Anti-arthritic
efficacy and safety of chrominex 3+ (trivalent chromium, Phyllanthus emblica,
extract, and Shilajit) in moderately arthritic dogs. . J. Vet. Sci. Anim. Husb.
1(4):1-6 (2014).
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Milatovic,
D., Gupta, R.C., Yu, Y, Zaja-Milatovic, S., and Aschner, M.: Protective effects
of antioxidants and anti-inflammatory agents against manganese-induced
oxidative damage and neuronal injury. Toxicol. Appl. Pharmacol. Special Issue
“Environmental Chemicals and Neurotoxicity”, 256:219-226 (2012).
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Gupta,
R.C., Canerdy, T.D., Lidley, J., Konemann, M., Minniear, J., Carroll, B.A.,
Hendrick, C., Goad, J.T., Rohde, K., Doss, R.B., Bagchi, M., and Bagchi, D.:
Comparative therapeutic efficacy and safety of type-II collagen (UC-II),
glucosamine and chondroitin in arthritic dogs: pain evaluation by ground force
plate. J. Anim. Physiol. Anim. Nutri. 96:770-777 (2011).
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Marone,
P.A., Lau, FC., Gupta, R.C., Bagchi, M., and Bagchi, D.: Safety and
toxicological evaluation of undenatured type II collagen. Toxicol. Mechan.
Methods. 20:175-189 (2010).
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Marone,
P.A., Yasmin, T., Gupta, R.C., and Bagchi, M.: Safety and toxicological evaluation
of AlgalCal(R) (AC), a novel plant-based calcium supplement. Toxicol. Mechan. Methods.
20: 334--344 (2010).
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Finkelstein,
Y., Milatovic, D., Lazarovici, P., Ophir, A., Richter, E.D., Aschner, M.,
Lecht, S., Marcinkiewicz, C., Lelkis, P.I., Zaja-Milatovic, S., Gupta, R.C.,
Brodsky, B., Rosengarten, A., Proscura, E., Shapira, E., and Wormser, U.:
Peaceful use of disastrous neurotoxicants. Neurotoxicology, 3451-3462 (2010).
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Milatovic,
D., Zaja-Milatovic, S., Gupta, R.C., Yu, Y., and Aschner, M.: Oxidative damage and
neurodegeneration in manganese-induced neurotoxicity. Toxicol. Appl. Pharmacol.
Special Issue “Toxicants and Neurodegenerative Diseases”, 240(2): 124-131
(2009).
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Zaja-Milatovic,
S., Gupta, R.C., Aschner, M., and Milatovic, D.: Protection of DFP-induced oxidative damage and neurodegeneration
by antioxidants and NMDA receptor antagonist. Toxicol. Appl. Pharmacol. Special
Issue “Toxicants and Neurodegenerative Diseases”, 240 (2): 219-225 (2009).
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Gupta,
R.C., Canerdy, T.D., Skaggs, P., Stocker, A, Zyrkowski, G., Burke, R., Wegford,
K., Goad, J.T., Barnett, D.,
DeWees, W., Bagchi, M., and Bagchi, D.: Therapeutic efficacy of undenatured
type-II collagen (UC-II) in comparison to glucosamine and chondroitin in arthritic
horses. J. Vet. Pharmacol. 32: 577-584 (2009).
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Zaja-Milatovic,
S., Gupta, R.C., Aschner, M., Montine, T.J., and Milatovic, D.: Pharmacologic
suppression of oxidative damage and dendritic degeneration following
kainic acid-induced excitotoxicity
in mouse cerebrum. Neurotoxicology. 29(4): 621-627 (2008).
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Gupta,
R.C. and Dekundy, A.: Donepezil or rivastigmine induced acetylcholinesterase Inactivation
is not modulated by neramexane in rat brain. Drug Dev. Res. 68:253-260 (2007).
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Gupta,
R.C., Milatovic, S., Dettbarn, W-D., Aschner, M. and Milatovic, D.:
Neuronal oxidative
injury and dendritic damage induced by carbofuran: Protection by memantine. Toxicol. Appl. Pharmacol.,
Special Issue “Anticholinesterases” 219 (2-3): 97-105 (2007).
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Liu,
J., Gupta, R.C., Goad, J.T., Karanth, S., and Pope, C.N.: Modulation of
parathion Toxicity by glucose feeding: Is nitric oxide involved? Toxicol. Appl.
Pharmacol. Special Issue
“Anticholinesterases” 219 (2-3): 106- 113 (2007).
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D’Altilio,
M., Peal, A., Alvey, M., Simms, C., Curtsinger, A. Gupta, R.C., Canerdy, T.D., Goad,
J.T., Bagchi, M., and Bagchi, D.: Therapeutic efficacy and safety of
undenatured type II collagen singly or in combination with glucosamine and
chondroitin in arthritic dogs. Toxicol. Mechan. Methods. 17: 189- 196 (2007).
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Jiang,
G.C.-T., Tidwell, K., McLaughlin, B.A., Cai, J., Gupta, R.C., Milatovic, D.,
Nass, R., And Aschner, M.: Neurotoxic potential of depleted uranium- Effects in
primary cortical neuron cultures and in Caenorhabditis elegans. Toxicol. Sci.:
553-565 (2007).
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Milatovic,
D., Yin, Z., Gupta, R.C., Sidoryk, M., Albrecht, J., Aschner, J.L., and
Aschner, M.: Manganese induces oxidative impairment in cultured rat astrocytes.
Toxicol. Sci. 98: 198-205 (2007).
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Peal,
A., D’Altilio, M., Simms, C., Alvey, M., Gupta, R.C., Goad, J.T., Canerdy,
T.D., Bagchi, M., and Bagchi, D.: Therapeutic efficacy and safety of
undenatured type-II collagen (UC-II) alone or in combination with
(-)-hydroxycitric acid and chromemate in arthritic dogs. J. Vet. Pharmacol.
Therap. 30: 275-278 (2007).
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Yang,
M.S., Tse, W.K.F., Yu, L.C., Li, K.M., Mak, N.K., and Gupta, R.C.: Energy and redox
states in the C6 glioma cells following acute exposure to Zn, Se+4 and Se+6 and
the correlation with apoptosis. Toxicol. Mechan. Methods. 16: 13-19 (2006).
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Gupta,
R.C., and Dekundy, A.: Memantine does not influence AChE inhibition in rat
brain by donepezil or
rivastigmine but does with DFP and metrifonate in in vivo studies. Drug Dev.
Res. 64: 71-81 (2005).
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DeParle,
L.A., Gupta, R.C., Canerdy, T.D., Goad, J.T., D’Altilio, M., Bagchi, M.,
and Bagchi, D.: Efficacy
and safety of glycosylated undenatured type-II collagen (UC-II)) in therapy of arthritic dogs. J.
Vet. Pharmacol. Therap. 28: 385-390 (2005).