Dr. Cesare Patrone

Karolinska Institute, Sweden

Email: Cesare.Patrone@ki.se

Qualifications

1998  Ph.D., Biotechnologies appli. to Pharmacology, Dept. of Pharmacological Sciences, Italy

Publications (Selected)

1. Zachrisson O, Zhao M, Andersson A, Dannaeus K, Häggblad J, Isacson R, Nielsen E, Patrone C, Rönnholm H, Wikstrom L, Delfani K, McCormack AL, Palmer T, Di Monte DA, Hill MP, Janson AM Haegerstrand A. Restorative effects of platelet derived growth factor‐BB in rodent models of Parkinson’s disease. Journal of Parkinson's diseases. In press (2011).
2. Isacson R, Nielsen E, Dannaeus K,Bertilsson G, Patrone C , Zachrisson O, WikströmL. Exendin‐4 stimulates hippocampal neurogenesis, induces antidepressant‐like effects and improves reference memory performance in adult rodents. European Journal of Neuroscience, Jan 10;650(1):249‐55 (2010).
3. Bertilsson G, Patrone C, Zachrisson O, Andersson A, Dannaeus K, Heidrich J, Kortesmaa J, Mercer A, Nielsen E, Rönnholm H, Wikström L. Peptide hormone exendin‐4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of Parkinson's disease. Journal of Neuroscience Research, 86(2):326‐38 (2008).
4. Hellström N, Zachrisson O, Kuhn G, Patrone C. Isolation, quantification and phenotypical characterization of adult mouse neural cells by flow cytometry. Letters in Drug Design & Discovery, 2007, 4, 532‐539 (2007).
5. Zachrisson O., Andersson A., Isacsson R., Mercer A., Nielsen A, Patrone C., Ronnoholm H, Wikstrom L., A. M. Janson, D. A. Di Monte, A. L. MC Cormack, T. D. Palmer, A. Haegestrand; Neurorestorative effects of PDGF‐BB in rodent models of Parkinson’s disease through stimulation of cell proliferation. Society for Neuroscience, 37th Annual meeting, San Diego. CA, USA, 2007
6. Patrone C. et al. Pharmacological activation of adult neural stem cells by Exendin‐4 as a potential treatment for Parkinson’s disease. Society for Neuroscience, 36th Annual Meeting, Atlanta, GA, USA, 2006.
7. Zachrisson O, Patrone C. et al. Pharmacological activation of endogenous stem cells by sNN0031 as a therapeutic strategy in Parkinson’s disease. Society for Neuroscience, 35th Annual Meeting, Washington, DC, USA, 2005.
8. Mercer A, Rönnolm H, Holmberg J, Lundh H, Heidrich J, Zachrisson O, Ossoinak A, Frisén J, Patrone C. PACAP promotes neural stem cell proliferation in the adult mouse brain. Journal of Neuroscience Research, 76:205–215, (2004).
9. Patrone C, Cassel TN, Petersson K, Maggi A., Warner M, Gustafsson J‐Å, Nord M Regulation of Postnatal Lung Development and Homeostasis by Estrogen Receptor β Molecular and Cell Biology. 23(23):8542‐52(2003).
10. Meda C., Vegeto E., Pollio G., Ciana P., Patrone C., Pellicciari C., Maggi A. Estrogen prevention of neural cell death correlates with decreased expression of the pro-apoptotic protein Nip‐2. Journal of Neuroendocrinology 12:(1051‐1059), (2000).
11. Patrone C, Pollio G, Enmark E, De Curtis E, Gustafsson J‐A, Maggi A. Estradiol induces differential neuronal phenotypes by activating ER α or ER βEndocrinology, 141(5):1839‐45, (2000).