Dr. Georges Nemer

American University of Beirut, Lebanon

Email:gn08@aub.edu.lb

Qualifications

2008 Associate Professor, American University of Beirut, Biochemistry and Molecular Genetics

2002  Ph.D., Universite de Montreal

1. Fahed A, Nemer G. Familial Hypercholesterolemia: The Lipids or the Genes? Nutrition and Metabolism (Accepted March 2011)
2. El-Hachem N, Nemer G. Identification of New GATA4-Small Molecule Inhibitors by Structure-Based Virtual Screening. Bioorganic and Medicinal Chemistry 19(5):1734-42 (2011)
3. Fahed AC, Safa RM, Haddad FF, Bitar FF, Andary RR, Arabi MT, Azar ST, Nemer G. Homozygous familial hypercholesterolemia in Lebanon: A genotype/phenotype correlation. Mol Genet Metab. 102(2):181-8 (2011)
4. Shaib H., Cochet N., Ribeiro T., Abdel Nour A., Nemer G., Barbour E. Pathogenicity and amino acid sequence variability in the HA1 protein of differently passaged H9N2 Avian Influenza virus. Medical Science Monitor 16(10):BR333-7 (2010)
5. Nemer G and Nemer M. Tbx5 et l’adaptation du cœur à la vie sur terre. Médecine-Sciences 26(8-9):699-700 (2010)
6. Hantouche C., Nemer G., Obeid M., Kadi L., Der-Boghossian H., Bikhazi A. Role of Glucagon-Like Peptide -1 (GLP-1) analogues on insulin receptor regulation in diabetic rat heart. Can. J. Physiol. Pharmacol. 88(1): 54–63 (2010)
7. Posch M., Gramlich M., Sunde M., Schmitt K., Panek A., Perrot A., Dietz R., Al-Khatib I, Nemer G. , Mégarbané A., Berger F., Harvey R., Özcelik C. A gain-of-function Tbx20 mutation causes human congenital cardiac atrial septal and valve defects. J Med Genet 47(4):230-5(2010)
8. Abou-Jawdah Y., Atamian H., Nemer G., Kfoury L.,Choukrallah N., Hanna L., Nemer N. Efficacy and molecular studies of a Lebanese isolate of Beauveria for the biocontrol of Thaumetopoea wilkinsoni (Lepidoptera : Thaumetopoeidae). Biocontrol Science & Technology. 18 (6):581-89 (2008)
9. Georges R *, Nemer G.*, Lefebvre C, Nemer M. Distinct Expression and Function of Alternatevily Spliced Tbx5 Isoforms in Cell Growth and Differentiation. Mol Cell Biol. 28(12):4052-67 (2008) (* Co-first author)
10. Hammud H., Nemer G., Sawma W., Touma J., Barnabe P., Bou-Mouglabey Y., Ghannoum A., El-Hajjar J., Usta J. Copper Adenine Complex, a compound, with multi-biochemical targets and potential anti-cancer effect. Chem Biol Interact. 28;173(2):84-96 (2008)
11. Nourredine L., Azzam R., Nemer G., Bielawski J., Nasser M., Bitar F., Dbaibo G. Modulation of total ceramide and constituent ceramide species in the acutely and chronically hypoxic mouse heart at different ages. Prostaglandins & Other Lipid Mediators 86(1-4):49-55 (2008).
12. Abdo, C., Nemer, N., Nemer G., Abou Jawdah, Y, and Kawar, N.S. Molecular identification of Beauveria spp. in Lebanon and evaluating its efficacy against the cedar web-spinning sawfly, Cephalcia tannourinensis. BioControl 53:341-352 (2008)
13. El-Rassi I., Bou-Abdallah J., Al-Ghadban S, Bitar F., Nemer G. Absence of NOTCH2 and Hey2 Mutations in a Familial Alagille Syndrome Case with a Novel FrameShift Mutation in JAG1. American Journal of Medical Genetics (A) 146(7):937-9 (2008)
14. Barada K., Nemer G., ElHajj I., Touma J.,Cortas N., Boustany RM,and Usta J. Early and severe liver disease associated with homozygosity for an exon 7 mutation, G691R, in Wilson's disease .Clinical Genetics 72(3):264-7 (2007)
15. Arabi M, Majdalani M, Nemer G, and Bitar F. Molecular markers of congenital heart disease. Congenital Cardiology Today 5(3):1-8 (2007)
16. Habib A., Shamseddeen I., Nasrallah M., Abi Antoun T., Nemer G., Bertoglio J., Badreddine R., and Badr K. Modulation of Cox-2 expression by statins in human monocytic cells. FASEB 21:1665-1674 (2007)
17. Yamak A, Karam P, Bitar F, Nemer G. Exclusive cardiac dysfunction in familial primary carnitine deficiency cases: a genotype-phenotype correlation. Clinical Genetics 72:59-62 (2007)
18. Lavallée G, Andelfinger G, Nadeau M, Lefebvre C, Nemer G, Horb M, Nemer M. KLF13, a novel GATA-4 cofactor and regulator of cardiogenesis. EMBO 25:5201-5213 (2006)
19. Yehya A, Souki R, Bitar F, and Nemer G. Differential Duplication of an Intronic Region in the NFATc1 Gene in Patients with Congenital Heart Disease. Genome 49(9):1092-1098 (2006)
20. Nemer G, Fadlalah F, Usta J, Nemer M,Dbaibo G, Obeid M, and Bitar F. A novel mutation in the GATA4 gene in patients with Tetralogy of Fallot. Human Mutation 27(3):293-4 (2006)
21. Alwani M, Usta J, Nemer G, El-Sabban M, Bitar H, Nasser M, Souki R, Dbaibo G, Bitar F. Regulation of the Sphingolipid Signaling Pathways in the Growing and Hypoxic Rat Heart. Prostaglandins & Other Lipid Mediators 78(1-4):249-63 (2005)
22. Abou-Jawdah Y, Sobh H, Cordahi N, Kawtharani H, Nemer G, Maxwell D, and Nakhla M : Immunodiagnosis of Prune dwarf virus using antiserum produced to its recombinant coat protein. J Virol Methods. 121(1):31-8 (2004)
23. Nemer G, Nemer M : Transcriptional activation of BMP-4 and regulation of mammalian organogenesis GATA-4 and GATA-6. Developmental Biology 254, 131-148 (2003)
24. Alison Brewer, Georges Nemer, Chris Gove, Francesca Rawlins, Mona Nemer, Roger Patient, John Pizzey : Widespread expression of an extended peptide sequence of GATA-6 during murine embryogenesis and non-equivalence of RNA and protein expression domains. Gene Expr Patterns. 2(1-2):123-3 (2002)
25. Nemer G and Nemer M : Cooperative interaction between GATA-5 and NF-ATc regulates endothelial-endocardial differentiation of cardiogenic cells. Development 129, 4045-4055 (2002)
26. Nemer G and Nemer M : Regulation of heart development and function through combinatorial interactions of transcription factors. Annals of Medicine 33, pp 604-610 (2001)

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Last Updated: August, 2012.

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