Dr. Giuseppe D’Antona

Email: gdantona@unipv.it

Qualifications

2004 Specialization in Sport Medicine, University of Pavia, Italy

2002 Post doctoral position, Department of Biomedical Science, University of Milano, Italy

2002 Ph.D., Physiology, University of Pavia, Italy

1996 M.D., University of Pavia, Italy

Publications (Selected)

1. Sampaolesi M, Torrente Y, Innocenzi A, Tonlorenzi R, D’Antona G, et al. Cell therapy of a-sarcoglycan null dystrophic mice through intra-arterial delivery of mesoangioblasts. Science 2003 301: 487-492
2. D'Antona G, et al. The effect of ageing and immobilization on structure and function of skeletal muscle fibres. J Physiol 2003 552: 499-511.
3. Pellegrino M A, Brocca L, Dioguardi FS, Bottinelli R, D'Antona G. Effects of voluntary wheel running and aminoacid supplementation on skeletal muscle of mice. Eur J Appl Physiol 2005 93(5-6): 655-64.
4. Gabellini D, D'Antona G, et al. Facioscapulohumeral muscular dystrophy in mice overexpressing FRG1. Nature 2006 439: 973-7.
5. D'Antona G et al. Skeletal muscle hypertrophy and structure and function of skeletal muscle fibres in male body builders. J Physiol 2006 570: 611-27.
6. Denti M, Rosa A, D’Antona G, et al. Body-wide gene therapy of Duchenne Muscular Dystrophy in the mdx mouse model. Proc Natl Acad Sci U S A 2006 103(10): 3758-63.
7. Sampaolesi M*, Blot S*, D’Antona G, et al. Rescue of muscular dystrophy pathology by mesoangioblast stem cells in Golden Retriever Dogs leads to preservation of motility. Nature 2006 444(7119): 574-9.
8. Brunelli S*, Sciorati C*, D’Antona G et al. Oral delivery of the NO-releasing drug HCT 1026 delays progression of muscular dystrophy and increases the efficacy of stem cell therapy. Proc Natl Acad Sci U S A 2007 104(1): 264-9.
9. D’Antona G, et al. Deterioration of contractile properties of muscle fibres in elderly subjects is modulated by the level of physical activity. Eur J Appl Physiol 2007 100(5):603-611.
10. D’Antona G, et al. Structural and functional alterations of muscle fibres in the novel mouse model of Facioscapulohumeral Muscular Dystrophy. J Physiol 2007 584.3:997-1011.
11. Brocca L, D'Antona G, Bachi A & Pellegrino MA. Amino acid supplements improve native antioxidant enzyme expression in the skeletal muscle of diabetic mice. Am J Cardiol 2008 101: 57E-62E.
12. Pansarasa O, Flati V, Corsetti G, Brocca L, Pasini E, D'Antona G. Oral amino acid supplementation counteracts age-induced sarcopenia in elderly rats. Am J Cardiol 2008 101: 35E-41E.
13. Pellegrino MA, Patrini C, Pasini E, Brocca L, Flati V, Corsetti G, D'Antona G. Amino acid supplementation counteracts metabolic and functional damage in the diabetic rat heart. Am J Cardiol 2008 101: 49E-56E.
14. Flati, F. Caliaro, S. Speca, G. Corsetti A. Cardile, E. Nisoli, R. Bottinelli, D’Antona G. Essential amino acids improve insulin activation of Akt/mTOR signalling in soleus muscle of aged rats. Int J Immunopathol. Pharmacol. 2010 23(1): 81-9.
15. D'Antona G, Nisoli E.mTOR signalling as a target of amino acid treatment of the age-related sarcopenia. Interdiscip. Top. Gerontol. 2010 37: 115-41.
16. D'Antona G, et al. Branched-chain amino acid supplementation promotes survival and supports cardiac and skeletal muscle mitochondrial biogenesis in middle-aged mice. Cell Metab. 2010 12(4): 362-72 (Journal Cover)