Dr. Bruce H. Francis

Eisai Inc., USA

Email: bruce_francis@eisai.com

Qualifications

1979 M.D., University of Bologna, Italy

1973 B.S., St. John’s University, USA

Publications (Selected)

1. Song, LM X. Andrews L. Francis B.H. et al. 2010 70th Annual ADA Meeting Healthcare Utilization and Costs among Pre-Diabetic Patients who Progress to Type 2 Diabetes Mellitus.
2. Banerji M, Purkayastha D, Francis BH  Safety and tolerability of vildagliptin vs. thiazolidinedione as add-on to metformin in patients with  Type 2 Diabetes with and without mild renal impairment. Aretrospecitie analysis of the GALIANT study. Diabetes Research and Clinical Practice. In press 2010.
3. M Banerji, D Purkayastha, B.H. Francis Safety of vildagliptin in patients with mild renal impairment and patients with normal renal function: GALIANT study. IDF 2009.
4. Murthy BP, Curtin CR, Vaccaro N, Doose DR, Wang SS, Abbot A, Francis BH, Fowler C, A Drug-Drug Interaction Study of the Pharmacokinetics of Topiramate and Glyburide and the Effects of Combination Therapy on Glycemic Control in Patients With Type-2 Diabetes Mellitus. Pharmacokinetics, Pharmacodynamics, and Drug Metabolism (PPDM) Section of the AAPS Annual Meeting 2005.
5. Frascella, DW, Kampa IS, Francis, BH: Temperature stress: a critical factor in the etiology of diabetes? Ed. Podolsky S, Raven Press, p563, New York.
6. Ensinck JW, Baskin DG, Vahl, Torsten P.,Vogel RE, Laschansky EC, Francis BH et al, Hoffman RC, Krakover JD, Stamm, MR, Low MJ, Rubinstein M, Otero-Corchon V, D’Alessio, DA. : Thrittene, homologous with somatostatin-28(1-13), is a novel peptide in Mammalian gut and circulation. Endocrinology 143(7):2599-2609, July 2002.
7. Aronoff S, Rosenblatt S, Braithwaite S, et al: Pioglitazone Hydrochloride Monotherapy improves glycemic control in the treatment of patients with Type 2 Diabetes; A 6 month randomized placebo-controlled dose-response study . Diabetes Care 23: 1605, 2000.
8. Schwartz S, Raskin P, Graveline JF et al: Effect of Troglitazone in Insulin Treated Patients with Type II Diabetes Mellitus. New England J Med. 338(13), 861, 1998.
9. Ensinck JW, Laschansky EC, Vogel RR, Francis, BH: Effect of ingested Carbohydrate, Fat and Protein on the release of Somatostatin 28 in Man. Gastroenterology, 98(3): 633, 1990.
10. Francis, BH, Baskin DG, Sanders D, Ensinck JW: Distribution of Somatostatin and Somatostatin 28 in Gastrointestinal-Pancreatic cells of Rat and Man. Gastroenterology, 99(5): 1283, 1990.