Author(s)

Xian Li, Xianglin Cheng^*

Department of Neurology, The Clinical Medicine School of Yangtze University, The First Affiliated Hospital of Yangtze University, Jingzhou, China.

Objective: To explore the application value of electrocardiograph (ECG) T-wave Alternans (TWA) anomaly in acute stage of intracerebral hemorrhage patients. Methods: We choose 1175 intracerebral hemorrhage patients whose conventional 12-lead ECG has TWA in our hospital from January 2011 to December 2015, 751 patients without TWA in the same period as the control group, compared the volume of intracerebral hemorrhage, bleeding site and mortality between the 2 groups. Results: In TWA group, 247 cases died, 361 cases with massive intracerebral hemorrhage, 298 cases with brain stem hemorrhage; in TWA negative group (control group), 41 cases died, 93 cases with massive brain hemorrhage, 64 cases with brain stem hemorrhage. There are statistical differences between two groups (P < 0.05). Multi factor Logistic regression analysis showed that massive intracerebral hemorrhage, brain stem hemorrhage, Glasgow score and TWA were the independent factors in the prognosis of intracerebral hemorrhage (P < 0.05). Conclusion: The occurrence of TWA is significantly related to the volume of bleeding, the bleeding site and mortality, and can be used as an important parameter in the prognosis of intracerebral hemorrhage.

Intracerebral Hemorrhage, T-Wave Alternans, Prognosis

Li, X. and Cheng, X. (2017) Application of T-Wave Alternans in Evaluation of Prognosis in Patients with Intracerebral Hemorrhage. Yangtze Medicine, 1, 127-132. doi: 10.4236/ym.2017.13013.