Metaplastic meningioma with pure and extensive cartilaginous transformation: A diagnostic dilemma


Meningiomas are the most common extra-axial central nervous system tumours and often discovered in the middle to late adult life and especially in women. About 85%-90% of meningiomas are benign, 5%-10% are intermediate-grade, and 3%-5% are malignant. Metaplastic meningioma is a rare subtype of WHO Grade I meningioma histologically characterized by the presence of mesenchymal components. The presence of pure and extensive cartilaginous differentiation in meningiomas is extremely rare and remains a diagnostic dilemma. We report, perhaps the first case of this entity in a 52-year-old woman and discuss the pathogenesis, the imaging features and the histopathologicals data.

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Coulibaly, O. , Onen, J. , Harmouch, A. , Boutarbouch, M. , Melhaoui, A. , Arkha, Y. , Rifi, L. , Derraz, S. , Sefiani, S. , Ouahabi, A. and Khamlichi, A. (2013) Metaplastic meningioma with pure and extensive cartilaginous transformation: A diagnostic dilemma. Case Reports in Clinical Medicine, 2, 390-394. doi: 10.4236/crcm.2013.27104.

Conflicts of Interest

The authors declare no conflicts of interest.


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