Xanthogranulomatous Pyelonephritis Associated with Crohn’s Disease and Primary Hyperparathyroidism

Mekdess Abebe, Wing Mu, Heesuck Suh, Edward P. Nord, Nand K. Wadhwa

Division of Nephrology, Department of Medicine, School of Medicine, State University of New York at Stony Brook, Stony Brook, USA.

DOI: 10.4236/ojneph.2013.33021                

Abstract

We report on a case of unilateral and diffuse xanthogranulomatous pyelonephritis (XGP) associated with Crohn’s disease and primary hyperparathyroidism (HPT). The patient had undiagnosed primary HPT for at least a year prior to presentation. The co-existence of Crohn’s disease and primary HPT caused calcium oxalate stone likely by the known mechanism of hypercalcemia and hyperoxaluria respectively. The patient developed XGP, a rare disease, as a result of infected calcium oxalate stone which was treated with antibiotics and unilateral nephrectomy. To the best of our knowledge, this is the first case of XGP associated with Crohn’s disease and primary HPT.

Keywords

Xanthogranulomatous Pyelonephritis; Hyperparathyroidism; Crohn’s; Hypercalcemia

Conflicts of Interest

The authors declare no conflicts of interest.

References

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