Assessment of Using Cosmetics Containing Hydroquinone among Sudanese Women

H. M. Osman^1*, M. E. Shayoub², Munzir M. E. Ahmed³, E. M. Babiker⁴

¹Department of Biochemistry, Faculty of Pharmacy, University of National Ribat, Khartoum, Sudan.
²Department of Pharmaceutics, Faculty of Pharmacy, University of Khartoum, Khartoum, Sudan.
³Department of Biochemistry, Faculty of Medicine, AL-Gadarif University, Gadarif, Sudan.
⁴Department of Zoology, Faculty of Sciences, University of Khartoum, Khartoum, Sudan.

DOI: 10.4236/jcdsa.2015.52009                

Abstract

Many countries in the world wide banned hydroquinone in cosmetics skin lightening but it is still used in most of Africa countries, including Sudan. Few studies were carried out on the side effect of hydroquinone on Sudanese women. Therefore, the present study was carried out in Khartoum state in April to May/2014 to assess the awareness of Sudanese women about using hydroquinone and its probable risks. The results revealed that, highly using cosmetics containing hydroquinone by women aged between 20 - 29 years (78.3%) as well as by those classified as single (69.6%). The results also showed that the highest percentage of women was using it during evening (81.2%) and a high percentage of them was using it for skin lightening (65.2%), followed by elimination acne (20.3%) and about 10.1% for both skin lightening and elimination of acne and very little (4.3%) for freckle elimination. Moreover, the results showed a very high percentage of women (94.2%) used the chemical without being prescribed by doctors and about (85.5%) of them didn’t know its nature and risks on human health. Consequently, (50.7%) of women have had sides effects, (44.9 %) used more than one and (44.1%) used it regularly. In addition, the results revealed that a wide range of products of this chemical was available in local market with amalico (34.8%) being highly used. The study can conclude that the awareness of Sudanese women about this compound was poor and needs to be raised by health authorities.

Keywords

Cosmetics, Side Effects, Hydroquinone, Skin Lightening

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1]	Gunter, S., SvenGohla, J., Whaltrand, K., Uwe Schonrock, H., Schmidt, L., Annegret, K., Xenia, P., Wolfgang, P., Hellmut, I. and Walter, D. (2005) Skin Cosmetics, in Ullmann’s Encyclopedia of Industrial Chemistry. Willey VCH, Weinheim, 280-285.
[2]	Priyanka, M., Ketki, D. and Hyacinth, H. (2013) Cytotoxic Effects of Benzene Metabolites on Human Sperm Function: An in Vitro Study. ISRN Toxicology, 2013, Article ID: 397524, 6pp.
[3]	Karamagi, E., Owino, E. and Katabira, E. (2001) Hydroquinone Neuropathy Following Use of Skin Bleaching Creams: Case Report. East African Medical Journal, 78, 223-224. http://dx.doi.org/10.4314/eamj.v78i4.9069
[4]	Us Food and Drug Administration (USFDA) (1992) FDA’s Cosmetics Handbook Washington DC, US Department of Health and Human Services, Public Health Service. Food and Drug Administration, 2, 21-23.
[5]	WHO. IPCS International Programme on Chemical Safety (1996) Health and Safety. Hydroquinone, Health and Safety Guide, No. 101, Rom.
[6]	Oyedeji, F., Hassan, G. and Adeleke, B. (2011) Hydroquinone and Heavy Metals Levels in Cosmetics Marketed in Nigeria. Trends in Applied Sciences Research, 6, 622-639. http://dx.doi.org/10.3923/tasr.2011.622.639
[7]	Vikas, B., Rajni, K., Arun, K. and Dinesh, K. (2014) A Novel Approach for Drug Delivery System. World Journal of Pharmaceutical Research, 3, 318-334.
[8]	Belezal, S. (2012) The Timing of Pigmentation Lightening in European. British Journal of Dermatology, 120, 229-238.
[9]	Lei, T., Virador, V., Vieira, W. and Hearing, V. (2002) A Melanocyte-Keratinocyte Coculture Model to Assess Regulators of Pigmentation in Vitro. Analytical Biochemistry, 305, 260-268. http://dx.doi.org/10.1006/abio.2002.5665