Human Immunodeficiency Virus Can Affect the Semiology of Osteoarticular Infections?


Objective: To compare the epidemiological, the clinical and the paraclinical profile of osteoarticular infections in HIV-positive patients and in HIV-negative patients. Patients and Methods: patients with Osteoarticular infections recognized on the basis of radioclinical and epidemiological arguments were included in this study. The comparison that was based on the existence or was not of HIV infection focused on various clinical and biological components. Of these 15,800 rheumatic patients admitted in 18 years, 461 have suffered from Osteoarticular infection (2.9%). The 461 patient objects of this study were divided into 235 cases of infectious arthritis including 38 cases of co-infection with HIV and 225 cases of infectious spondylodiscitis including 21 cases of HIV co-infection. Results: There were 246 women (53.4%) and 215 men (46.4%) with a sex ratio of 1.1. The mean age was 37.7 ± 13.6 years. The data comparison of HIV-negative patients and HIV-positive patients had not shown statistically significant difference in the infectious spondylodiscitis group and in the group of infectious arthritis patients. Only fever was statistically significant in both groups and weight loss in the group of infectious arthritis (p < 0.001). Conclusion: HIV seems not to particularly influence the semiological profile of Osteoarticular infections in Lomé.

Share and Cite:

Oniankitan, O. , Tagbor, K. , Kakpovi, K. , Fianyo, E. , Houzou, P. , Koffi-Tessio, V. and Mijiyawa, M. (2014) Human Immunodeficiency Virus Can Affect the Semiology of Osteoarticular Infections?. Open Journal of Rheumatology and Autoimmune Diseases, 4, 235-239. doi: 10.4236/ojra.2014.44032.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Yao, Q., Frank, M., Glynn, M. and Altman, R.D. (2008) Rheumatic Manifestations in HIV-1 Infected In-Patients and Literature Review. Clinical and Experimental Rheumatology, 26, 799-806.
[2] Rogeaux, O., Fassin, D. and Gentilini, M. (1993) Prevalence of Rheumatic Manifestations in Human Immunodeficiency Virus Infection. Annales de Médecine Interne, 144, 443-448.
[3] Saraux, A., Jousse, S., Roudant, A. and Devuchelle, V. (2006) Particularites des infections osteoarticulaires chez les sujets VIH positifs et les toxicomanes. Revue du Rhumatisme, 73, 163-167.
[4] Njobvu, P., Mcgill, P., Kerr, H. and Poppee, J. (1998) Spondylarthropathy and Human Immunodeficiency Virus Infection in Zambia. The Journal of rheumatology, 25, 1553-1559.
[5] Kaddu-Mukasa, M., Ssekasanvu, E., Ddumba, E., Thomas, D. and Katabira, E.T. (2011) Rheumatic Manifestations among HIV Positive Adults Attending the Infectious Disease Clinic at Mulago Hospital. African Health Sciences, 11, 24-29.
[6] Reveille, J.D. and Williams, F.M. (2006) Infection and Musculoskeletal Conditions: Rheumatologic Complications of HIV Infection. Best Practice & Research. Clinical Rheumatology, 20, 1159-1179.
[7] Ventura, G., Gasparini, G., Lucia, M.B., Tumbarello, M., Tacconelli, E., Caldarola, G., et al.. (1997) Osteoarticular Bacterial Infections Are Rare in HIV-Infected Patients.14 Cases founds among 4023 HIV-Infected Patients. Acta Orthopaedica Scandinavica, 68, 554-558.
[8] Marquez, J., Restrepo, C.S., Candia, L., Berman, A. and Espinoza, L.R. (2004) Human Immunodeficiency Virus-Associated Rheumatic Disorders in the HAART Era. The Journal of rheumatology, 31, 741-746
[9] Louthrenoo, W. (2008) Rheumatic Manifestations of Human Immunodeficiency Virus Infection. Current Opinion in Rheumatology, 20, 92-99.
[10] Munoz-Fernandez, S., Cardenal, A., Balsa, A., Quiralte, J., del Arco, A., Pena, J.M., et al. (1991) Rheumatic Manifestations in 556 Patients with Human Immunodeficiency Virus Infection. Seminars in Arthritis and Rheumatism, 21, 30- 39.
[11] Berman, A., Espinoza, L.R., Diaz, J.D., Aguilar, J.L., Rolando, T., Vasey, F.B., et al. (1988) Rheumatic Manifestations of Human Immunodeficiency Virus Infection. The American Journal of Medicine, 85, 59-64.
[12] Busch, V.J., Regez, R.M., Heere, B. and Willems, W.J. (2007) Osteoarticular Infections in HIV-Infected Patients: 23 Cases among 1515 HIV-Infected Patients. Acta Orthopaedica, 78, 786-790.
[13] Schulzer, M., Fitzgerald, J.M., Enarson, D.A. and Grzybowski, S. (1992) An Estimate of the Future Size of the Tuberculosis Problem in Sub-Sahara Africa, Resulting from HIV Infection. Tubercle and Lung Disease, 73, 52-58.
[14] Meddeb, N., Rammeh, N., Chahed, M., Sahli, H., Elleuch, M., Cheour, E., Zouari, B. and Sellmi, S. (2002) Aspects actuels du mal de Pott en Tunisie. A propos d’une série de 29 cas. Bulletin de la Société de pathologie exotique, 95, 269-271.
[15] Jellis, J.E. (1996) Orthopaedic Surgery and HIV Disease in Africa. International Orthopaedics, 20, 253-256.
[16] CDC (1994) Revised Classification System for Human Immunodeficiency Virus Infection in Children Less than 13 Years of Age. Morbidity and Mortality Weekly Report, 43, 1-10.
[17] Jellis, J.E. (2002) Human Immunodeficiency Virus and Osteoarticular Tuberculosis. Clinical Orthopaedics and Related Research, 398, 27-31.
[18] Larget-Piet, B. and Martigny, J. (1995) Bacterial Spondylodiscitis. Etiology, Diagnosis, Development, Prognosis, Treatment. Revue du praticien, Paris, 45, 915-920.
[19] Maftah, M., Lmejjati, M., Mansouri, A., El Abbadi, N. and Bellakhdar, F. (2001) Mal de Pott. A propos de 320 cas. Médecine du Maghreb, 90, 19-22.
[20] Sakho, Y., Badiane, S.B., N’Dao, A.K., N’Diaye, A., Gueye, M. and N’Diaye, I.P. (2003) Pott’s Disease in Senegal. European Journal of Orthopaedic Surgery & Traumatology, 13, 13-20.
[21] Oniankitan, O., Bagayogo, Y., Fianyo, E., Koffi-Tessio, V., Kakpovi, K., Tagbor, K.C., et al. (2009) Spondylodiscitis at a Hospital Outpatient Clinic in Lome, Togo. Médecine Tropicale: Revue du Corps de Santé Colonial, 69, 581-582.
[22] Bileckot, R. and Miakoundoba, R.C. (2007) Aspects bactériologiques et évolutifs des arthrites septiques à Brazaville. Bulletin de la Société de pathologie exotique, 100, 308.
[23] Ntsiba, H., Bazébissa, R., Lamini, N. and Yala, F. (2004) Cent cas d’arthrites septiques du genou en zone intertropicale. Bulletin de la Société de pathologie exotique, 97, 244-246.
[24] Oniankitan, O., Bagayogo, Y., Fianyo, E., Koffi-Tessio, V., Kakpovi, K., Tagbor, K.C., Houzou, P. and Mijiyawa, M. (2011) Infectious Arthritis in Hospital Patients in Lomé, Togo. Médecine Tropicale: Revue du Corps de Santé Colonial, 71, 61-62.
[25] Bileckot, R., Ntsiba, H., Okong, D. and Ognami, J.B. (1994) Arthritis in Black Africa: A Review of 473 Cases Seen in Congo. Revue du Rhumatisme, 61, 260-265.

Copyright © 2022 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.