Iatrogenic calcinosis cutis in a child affected by Acute Lymphoblastic Leukemia

DOI: 10.4236/crcm.2014.31004   PDF   HTML   XML   3,728 Downloads   5,005 Views  

Abstract

Iatrogenic calcinosis cutis is a rare disorder that can be due to the intravenous administration of calcium or phosphate-containing infusions such as calcium gluconate or calcium chloride with extravasation. Fortunately, the course of calcinosis cutis is benign in immunocompetent children. The treatment remains supportive therapy. After about 6 months, there is no evidence of tissue calcification. We describe a 4-year-old girl with Acute Lymphoblastic Leukemia (ALL) who developed severe calcinosis cutis in the left humerus after extravasation of calcium gluconate during the treatment for the tumor-lysissyndrome-related hypocalcaemia. Surgical debridement and local wound care were not successful, and so a temporary suspension of chemotherapy was necessary to achieve complete healing of the lesion. Notwithstanding this complication, her ALL is in complete hematological remission after 8 months from the diagnosis. No functional or sensitive impairment due to the cutis has persisted.

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Perillo, T. , Arcamone, G. , Bonamonte, D. , Pascone, M. and Santoro, N. (2014) Iatrogenic calcinosis cutis in a child affected by Acute Lymphoblastic Leukemia. Case Reports in Clinical Medicine, 3, 13-17. doi: 10.4236/crcm.2014.31004.

Conflicts of Interest

The authors declare no conflicts of interest.

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