A case of recurrent rhabdomyolysis associated with childhood Sjögren’s syndrome

Shuntaro Morikawa, Ichiro Kobayashi, Yutaka Uzuki, Masahiro Ueki, Tetsuo Hattori, Hayato Aoyagi

Department of Pediatrics, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Department of Pediatrics, Obihiro Kyokai Hospital, Obihiro, Japan.

DOI: 10.4236/ojped.2013.33049                

Abstract

We report a 9-year-old Japanese girl who presented with muscle weakness and elevated serum levels of muscle-derived enzymes following mycoplasma infection. Rhabdomyolysis or myositis was suggested by magnetic resonance imaging and repeated four times within 4 years. Each episode developed following respiratory infection and spontaneously recovered. The diagnosis of Sjogren’s syndrome was made by decreased salivary secretion, MR sialography, lip biopsy, and positive anti-SSA/Ro antibody. Given the rarity of rhabdomyolysis/myositis, recurrent episode could be induced by infectious disease on the basis of underlying Sjogren’s syndrome. Conclusion: Sjogren’s syndrome should be considered as an underlying disease of recurrent infection-induced rhabdomyolysis/ myositis.

Keywords

: Childhood; Infection; Myositis; Mycoplasma Pneumoniae; Sjögren’s Syndrome

Conflicts of Interest

The authors declare no conflicts of interest.

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