First Results of ACH Cardioplegic Solution Clinical Application in Newborns and Infants under One Year of Age

DOI: 10.4236/wjcd.2013.35A006   PDF   HTML     2,692 Downloads   4,040 Views   Citations

Abstract

Study objective involved comparison of two cardioplegic solutions: HTK-solution possessing high buffer capacity and a new ACH-solution with aminoacid buffer. Results revealed high cardioprotective efficiency during surgical repair of complex congenital heart disease both in the group that had received Custodiol and in the group that had received ACH-solution. Clinical and morphological parameters demonstrate high level of myocardial protection from intraoperative ischemia for single usage of ACH-solution during cardioplegic ischemia under 60 minutes in duration.

Share and Cite:

Bockeria, L. , Boldyrev, A. , Kulaga, O. , Blejyants, G. , Egorov, D. , Popov, A. , Mumladze, K. , Egorova, I. , Artuhina, T. , Kalaeva, N. and Movsesian, R. (2013) First Results of ACH Cardioplegic Solution Clinical Application in Newborns and Infants under One Year of Age. World Journal of Cardiovascular Diseases, 3, 33-39. doi: 10.4236/wjcd.2013.35A006.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] Cruz, D.N., Antonelli, M., Fumagalli, R., et al. (2009) Early use of polymyxin B hemoperfusion in abdominal septic shock. JAMA, 301, 2445-2452.
[2] Reithmann, C., Reber, D., Kozlik-Feldmann, R., et al. (1997) A post-receptor defect of adenylyl cyclase in severely failing myocardium from children with congenital heart disease. European Journal of Pharmacology, 330, 79-86.
[3] Ross, R.D. (2001) Grading the graders of congestive heart failure in children. Journal of Pediatrics, 138, 618-620.

  
comments powered by Disqus

Copyright © 2020 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.