Hyper-Miniaturisation of Monodisperse Janus Hydrogel Beads with Magnetic Anisotropy Based on Coagulation of Fe3O4 Nanoparticles

DOI: 10.4236/msce.2013.12001   PDF   HTML   XML   3,807 Downloads   7,744 Views   Citations


We describe a simple and robust technique for fabricating monodisperse Janus hydrogel beads with magnetic anisotropy smaller than the microchannel used to produce them.

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Aketagawa, K. , Hirama, H. and Torii, T. (2013) Hyper-Miniaturisation of Monodisperse Janus Hydrogel Beads with Magnetic Anisotropy Based on Coagulation of Fe3O4 Nanoparticles. Journal of Materials Science and Chemical Engineering, 1, 1-5. doi: 10.4236/msce.2013.12001.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] A. Ghosh, N. K. Sheridon and P. Fischer, “Voltage-Controllable Magnetic Composite Based on Multifunctional Polyethylene Microparticles,” Small, Vol. 4, No. 11, 2008, pp. 1956-1958. doi:10.1002/smll.200701301
[2] S. N. Yin, C. F. Wang, Z. Y. Yu, J. Wang, S. S. Liu and S. Chen, “Versatile Bifunctional Magnetic-Fluorescent Responsive Janus Supraballs towards the Flexible Bead Display,” Advanced Materials, Vol. 23, No. 26, 2011, pp. 2915-2919.
[3] R. K. Shah, J. Kim and D. A. Weitz, “Janus Supraparticles by Induced Phase Separation of Nanoparticles in Droplets,” Advanced Materials, Vol. 21, No. 19, 2009, pp. 1949-1953.
[4] N. Zhao and M. Y. Gao, “Magnetic Janus Particles Prepared by a Flame Synthetic Approach: Synthesis, Characterizations and Properties,” Advanced Materials, Vol. 21, No. 2, 2009, pp. 184-187.
[5] A. K. F. Dyab, M. Ozmen, M. Ersoz and V. N. Paunov, “Fabrication of Novel Anisotropic Magnetic Microparticles,” Journal of Materials Chemistry, Vol. 19, No. 21, 2009, pp. 3475-3481. doi:10.1039/b814971m
[6] K. P. Yuet, D. K. Hwang, R. Haghgooie and P. S. Doyle, “Multifunctional Superparamagnetic Janus Particles,” Langmuir, Vol. 26, No. 6, 2010, pp. 4281-4287. doi:10.1021/la903348s
[7] L. B. Zhao, L. Pan, K. Zhang, S. S. Guo, W. Liu, Y. Wang, Y. Chen, X. Z. Zhao and H. L. W. Chan, “Generation of Janus Alginate Hydrogel Particles with Magnetic Anisotropy for Cell Encapsulation,” Lab on a Chip, Vol. 9, No. 20, 2009, pp. 2981-2986. doi:10.1039/b907478c
[8] Y. J. Zhao, H. C. Shum, H. S. Chen, L. L. A. Adams, Z. Z. Gu and D. A. Weitz, “Microfluidic Generation of Multifunctional Quantum Dot Barcode Particles,” Journal of the American Chemical Society, Vol. 133, No. 23, 2011, pp. 8790-8793. doi:10.1021/ja200729w
[9] C. H. Chen, A. R. Abate, D. Y. Lee, E. M. Terentjev and D. A. Weitz, “Microfluidic Assembly of Magnetic Hydrogel Particles with Uniformly Anisotropic Structure,” Advanced Materials, Vol. 21, No. 31, 2009, pp. 3201-3204.
[10] Y. Lee, S. Lee, J.-B. Kwak, S. Kim, H.-Y. Cha, C. H. Lee, C. S. Lee and H.-S. Lee, “Friction Effect on the Rotation of Bichromal Ball in a Monolayer Rotating Ball Display,” Journal of Applied Physics, Vol. 108, 2010, Article ID: 102812. doi:10.1063/1.3511710
[11] W. H. Tan and S. Takeuchi, “Monodisperse Alginate Hydrogel Microbeads for Cell Encapsulation,” Advanced Materials, Vol. 19, No. 18, 2007, pp. 2696-2701. doi:10.1002/adma.200700433
[12] T. Nisisako and T. Torii, “Formation of Biphasic Janus Droplets in a Microfabricated Channel for the Synthesis of Shape-Controlled Polymer Microparticles,” Advanced Materials, Vol. 19, No. 11, 2007, pp. 1489-1493.
[13] D. R. Link, E. Grasland-Mongrain, A. Duri, F. Sarrazin, Z. D. Cheng, G. Cristobal, M. Marquez and D. A. Weitz, “Electric Control of Droplets in Microfluidic Devices,” Angewandte Chemie-International Edition, Vol. 45, No. 16, 2006, pp. 2556-2560. doi:10.1002/anie.200503540
[14] H. Kim, D. W. Luo, D. Link, D. A. Weitz, M. Marquez, and Z. D. Cheng, “Controlled Production of Emulsion Drops Using an Electric Field in a Flow-Focusing Microfluidic Device,” Applied Physics Letters, Vol. 91, No. 13, 2007, Article ID: 133106. doi:10.1063/1.2790785
[15] T. Nisisako, T. Torii and T. Higuchi, “Novel MicroreacTors for Functional Polymer Beads,” Chemical Engineering Journal, Vol. 101, No. 1-3, 2004, pp. 23-29. doi:10.1016/j.cej.2003.11.019
[16] H. M. Wyss, D. L. Blair, J. F. Morris, H. A. Stone and D. A. Weitz, “Mechanism for Clogging of Microchannels,” Physical Review E, Vol. 74, No. 6, 2006, Article ID: 061402. doi:10.1103/PhysRevE.74.061402
[17] T. Nisisako, T. Torii, T. Takahashi and Y. Takizawa, “Synthesis of Monodisperse Bicolored Janus Particles with Electrical Anisotropy Using a Microfluidic Co-Flow System,” Advanced Materials, Vol. 18, No. 9, 2006, pp. 1152-1156. doi:10.1002/adma.200502431
[18] S. Ahn, D. W. Kim, Y. W. Kim and J. Y. Yoo, “Generation of Janus Droplets for Enhanced Mixing in Microfluidics,” International Journal of Precision Engineering and Manufacturing, Vol. 11, No. 5, 2010, pp. 799-802. doi:10.1007/s12541-010-0095-z
[19] H. Hirama, T. Kambe, K. Aketagawa, T. Ota, H. Moriguchi and T. Torii, “Hyper Alginate Gel Microbead Formation by Molecular Diffusion at the Hydrogel/Droplet Interface,” Langmuir, Vol. 29, No. 2, 2013, pp. 519-524. doi:10.1021/la303827u
[20] K. Aketagawa, H. Hirama, H. Moriguchi and T. Torii, “Fabrication of Titania Microspheres Using Alginate Microdroplets on an Oil/Hydrogel Interface,” The 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Seattle, 2-6 October 2011, pp. 1615-1617.
[21] K. Aketagawa, H. Hirama, H. Moriguchi and T. Torii, “Janus Hydrogel Beads for Electronic Paper Using Shrinkage-Gelation Technique,” The 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Okinawa, 28 October-1 November 2012, pp. 890-892.
[22] L. X. Wen and K. D. Papadopoulos, “Effects of Osmotic Pressure on Water Transport in W-1/O/W-2 Emulsions,” Journal of Colloid and Interface Science, Vol. 235, No. 2, 2001, pp. 398-404. doi:10.1006/jcis.2000.7384
[23] J. Cheng, J. F. Chen, M. Zhao, Q. Luo, L. X. Wen and K. D. Papadopoulos, “Transport of Ions through the Oil Phase of W-1/O/W-2 Double Emulsions,” Journal of Colloid and Interface Science, Vol. 305, No. 1, 2007, pp. 175-182. doi:10.1016/j.jcis.2006.09.055
[24] G. Talei Franzesi, B. Ni, Y. Ling and A. Khademhosseini, “A Controlled-Release Strategy for the Generation of Cross-Linked Hydrogel Microstructures,” Journal of the American Chemical Society, Vol. 128, No. 47, 2006, pp. 15064-15065.
[25] D. Saeki, S. Sugiura, T. Kanamori, S. Sato and S. Ichikawa, “Microfluidic Preparation of Water-in-Oil-in-Water Emulsions with an Ultra-Thin Oil Phase Layer,” Lab on a Chip, Vol. 10, No. 3, 2010, pp. 357-362. doi:10.1039/b916318b
[26] R. J. Hunter, “Foundations of Colloid Science,” Oxford University Press, Oxford, 2001.
[27] W. Kunz, J. Henle and B. W. Ninham, “‘Zur Lehre von der Wirkung der Salze’ (about the Science of the Effect of Salts): Franz Hofmeister’s Historical Papers,” Current Opinion in Colloid & Interface Science, Vol. 9, No. 1, 2004, pp. 19-37. doi:10.1016/j.cocis.2004.05.005

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