Vulvar dystrophies: A long-term Brisbane study of 155 cases ()
Ian S. C. Jones,
Alister Jones
Department of Surgery, Gold Coast Hospital, Gold Coast, Australia.
Women’s and Newborn Services, Royal Brisbane and Women’s Hospital, Brisbane and University of Queensland, and Department of Surgery, Gold Coast Hospital, Southport, Queensland, Australia.
DOI: 10.4236/ojog.2012.23042
PDF
HTML
5,294
Downloads
7,637
Views
Citations
Abstract
Objective: To review the long-term outcomes for 155 women with a vulvar dystrophy (VD) who attended the Royal Brisbane Hospital Vulvar Clinic between 1976 and 1988. Methods: VD data from Vulvar Diseases Clinic were reviewed and analysed using the computer software Statistical package for the Social Sciences (SPSS) 11.0. Results: Of 155 patients 94 had Lichen Sclerosus (LS), 41 Lichen Simplex Chronicus (LSC) and 20 Mixed Dystrophy (MD). Three patients developed squamous cell carcinomas of the vulva between 10 and 26 years after presentation with a VD. To date only one of these three patients remains alive following treatment. Conclusion: The need for long term follow up is stressed and any of the three types of VD may become malignant. Time from diagnosis to malignant change is not predictive. VD treatments seem to go through phases with the application of potent steroid creams having stood the test of time.
Share and Cite:
Jones, I. and Jones, A. (2012) Vulvar dystrophies: A long-term Brisbane study of 155 cases.
Open Journal of Obstetrics and Gynecology,
2, 210-212. doi:
10.4236/ojog.2012.23042.
Conflicts of Interest
The authors declare no conflicts of interest.
References
|
[1]
|
O’Connell, T.X., Nathan, L.S., Satmary, W.A. and Goldstein, A.T. (2008) Non-neoplastic epithelial disorders of the vulva. American Family Physician, 77, 321-326.
|
|
[2]
|
Maclean, A.B. (1991) Vulval dystrophy—The passing of a term. Current Obstetrics & Gynaecology, 1, 97-102.
doi:10.1016/0957-5847(91)90038-Y
|
|
[3]
|
Neill, S. and Lewis, F. (2009) Ridley’s the vulva. 3rd Edition, Wiley-Blackwell, Hoboken.
|
|
[4]
|
Smith, Y.R. and Haefner, H.K. (2004) Vulvar lichen sclerosus: Pathophysiology and treatment. American Journal of Clinical Dermatology, 5, 105-125.
doi:10.2165/00128071-200405020-00005
|
|
[5]
|
Scurry, J.P. and Vanin, K. (1997) Vulvar squamous cell carcinoma and lichen sclerosus. The Australasian Journal of Dermatology, 38, S20-S25.
|
|
[6]
|
Ayhan, A., Guvendag Guven, E.S., Guven, S., Sakinci, M. and Kucukali, T. (2006) Medical treatment of vulvar squamous cell hyperplasia. International Journal of Gynaecology & Obstetrics, 95, 278-283.
doi:10.1016/j.ijgo.2006.06.024
|