Concomitant H1N1 encephalopathy and acute ischemic stroke: A case report

Abstract

Neurological complications of infection by the novel H1N1 virus have been described primarily in children. In adults, patients typically present with fever and respiratory symptoms, and may develop acute respi-ratory distress syndrome, sepsis and stroke. We present a 45-year-old man whose presentation of aphasia and right hemiplegia were incongruent with the findings on MRI of a small acute ischemic stroke. He rapidly developed multi-organ failure and died. Nasal swab PCR obtained prior to death returned positive for influenza virus A/H1N1. At autopsy, a small acute hemorrhagic infarction in the left parietal lobe was present. We suspect that this was a car-dio-embolic stroke, probably triggered by H1N1 myocarditis.

Share and Cite:

Wirkowski, E. , Yasen, J. and Bondoc, C. (2012) Concomitant H1N1 encephalopathy and acute ischemic stroke: A case report. World Journal of Cardiovascular Diseases, 2, 99-101. doi: 10.4236/wjcd.2012.22016.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] Webster, R.I., Hazelton, B., Suleiman, J., MaCartney, K., Kesson A. and Dale R.C. (2010) Infection in childhood: Case reports severe encephalopathy with swine origin influenza a H1N1. Neurology, 74, 1077-1078.
[2] Uyeki, T., “Diagnostic testing for 2009 pandemic influenza a (H1N1) virus infection in hospitalized patients, The New England Journal of Medicine, 361, e114.
[3] Tan, K., Prerna, A. and Leo, Y.S. (2010) Surveillance of H1N1-related neurological complications. The Lancelet, 9, 142-143. doi:10.1016/S1474-4422(10)70015-6
[4] Libman, R. and Wirkowski, E. (1995) Conditions that mimic stroke in the emergency room, Archives of Neurology, 52, 1119-1122. doi:10.1001/archneur.1995.00540350113023
[5] Bowles, N.E. and Kearney, D.L. (2003) Detection of viruses in myocardial tissue by PCR, evidence of adenovirus as a common causeof myocarditis in children and adults. Journal of the American College of Cardiology, 42, 466- 472 doi:10.1016/S0735-1097(03)00648-X
[6] Kitcharoen, S., Pattapongsin, M., Sawanyawisuth, K., Vincent, A. and Tiamkao, S. (2010) Neurologic manifestations of pandemic (H1N1) virus infection. Emerging Infectious Diseases, 16, 569-570. doi:10.3201/eid1603.091699

Copyright © 2024 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.