The Challenges of Diagnosing Disseminated Lyme Disease in a Patient with CLL

DOI: 10.4236/ojbd.2012.21003   PDF   HTML   XML   4,911 Downloads   8,072 Views  

Abstract

The diagnosis of Lyme disease may be a challenge in patients with Chronic Lymphocytic Leukemia. In relying on detection of antibodies in the serum for diagnosis we are presented with a problem in our patients with CLL in whom there is hypogammaglobulinemia secondary to B-cell malfunction. We suggest the use of PCR in aiding in diagnosis of Lyme disease in patients with CLL.

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S. Futuri, A. Malik and D. Shani, "The Challenges of Diagnosing Disseminated Lyme Disease in a Patient with CLL," Open Journal of Blood Diseases, Vol. 2 No. 1, 2012, pp. 14-15. doi: 10.4236/ojbd.2012.21003.

Conflicts of Interest

The authors declare no conflicts of interest.

References

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[2] M. Kalac, et al., “Central Nervous System Involvement of Previously Undiagnosed Chronic Lymphocytic Leukemia in a Patient with Neuroborreliosis,” International Journal of Hematology, Vol. 85, No. 4, 2007, pp. 323-325. doi:10.1532/IJH97.E0618
[3] L. Cerroni, et al., “Specific Cutaneous Infiltrates of B-Cell Chronic Lymphocytic Leukemia (B-CLL) at Sites Typical for Borrelia burgdorferi Infection,” Journal of Cutaneous Pathology, Vol. 29, No. 3, 2002, pp. 142-147. doi:10.1034/j.1600-0560.2002.290303.x

  
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