Transplacental transmission of EDTA dependent pseudothrombocytopenia in a neonate

Abstract

Verifying platelet counts can prevent unwarranted diagnostic tests and transfusions. In case of thrombocytopenia, if the clinical picture and history do not suggest bleeding tendency, one should always perform peripheral blood smear by directly obtaining blood by finger puncture before doing any further tests. If the peripheral blood smear exhibits platelet clumps, pseudothrombocytopenia should always be remembered. In this case, we present a neonate with a diagnosis of transplacental transmission of EDTA-dependant pseudothrombocytopenia.

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Bay, A. , Sivasli, E. , Taviloglu, S. , Leblebisatan, G. , Coskun, E. and Uluca, U. (2011) Transplacental transmission of EDTA dependent pseudothrombocytopenia in a neonate. Open Journal of Pediatrics, 1, 39-40. doi: 10.4236/ojped.2011.13011.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] Onder, O., Weinstein, W. and Hoyer, L.W. (1980) Pseu- do-thrombocytopenia caused by platelet agglutinins that are reactive in blood anticoagulated with chelating agents. Blood, 56, 177-182.
[2] Said, S.M., Hahn, J., Schleyer, E., Müller, M., Fiedler, G.M., Buerke, M. and Prondzinsky, R. (2007) Glyco-protein IIb/IIIa inhibitor-induced thrombocytopenia: Di-agnosis and treatment. Clinical Research in Cardiology, 96, 61-69. doi:10.1007/s00392-006-0459-7
[3] Van der Meer, W., Allebes, W., Simon, A., Van Berkel, Y. and De Keijzer, M.H. (2002) Pseudothrombocytopenia: A report of a new method to count platelets in a patient with EDTA-and temperature-independent antibodies of the IgM type. European Journal of Haematology, 69, 243-247. doi:10.1034/j.1600-0609.2002.02680.x
[4] Zandeck?, M., Genev?eve, F., Gerard, J. and Godon, A. (2007) Spurious counts and spurious results on haema-tology analysers: A review. Part I: Platelets. International Journal of Laboratory Hematology, 29, 4-20.
[5] Chiurazzi, F., Villa, M.R. and Rotoli, B. (1999) Trans-placental transmission of EDTA-dependent pseudothrom- bocytopenia. Haematologica, 84, 664.
[6] Akbayram, S., Dogan, M., Akgun, C., Caksen, H. and Oner, A.F. (2010) EDTA-dependent pseudothrombocy-topenia in a child. Clinical and Applied Thrombosis He-mostasis, 7 June 2010 (ahead of print).

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